Overlapping Single Molecule High-Fidelity Sequencing Data (CROSBI ID 434093)
Ocjenski rad | diplomski rad
Podaci o odgovornosti
Babojelić, Dario
Šikić, Mile
engleski
Overlapping Single Molecule High-Fidelity Sequencing Data
Recently, Pacific Biosciences improved their sequencing chemistry and sequencer performance, which resulted in a novel protocol enabling high- fidelity (HiFi) fragments. These single molecule real-time HiFi reads offer high accuracy while maintaining the length of longer reads. Current state of the art software for analyzing DNA reads were not developed to utilize that. The main subject of this thesis is exploiting the length and accuracy of HiFi reads. New methods, which adapt less sensitive approaches, for finding overlaps and mapping of DNA HiFi reads are explored and tested
bioinformatics ; DNA reads ; overlap ; map ; PacBio ; HiFi ; minimizer
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Podaci o izdanju
35
13.07.2020.
obranjeno
Podaci o ustanovi koja je dodijelila akademski stupanj
Fakultet elektrotehnike i računarstva
Zagreb