Complete Response of Adult-Onset CNS Langerhans Cell Histiocytosis Documented on 18F-FDG PET/CT (CROSBI ID 282006)
Prilog u časopisu | kratko priopćenje | međunarodna recenzija
Podaci o odgovornosti
Kruljac, Ivan ; Balenović, Antonija ; Imashuku, Shinsaku ; Vrkljan, Milan
engleski
Complete Response of Adult-Onset CNS Langerhans Cell Histiocytosis Documented on 18F-FDG PET/CT
We report a case of a 49-year-old woman with biopsy-proven multisystemic Langerhans cell histiocytosis (LCH) with hypothalamic involvement documented on F-FDG PET/CT. Chemotherapy with a combination of vinblastine, prednisolone, methotrexate, and 6- mercaptopurine was carried out. Two months later, a 90% reduction of the hypothalamic tumor mass was noted on magnetic resonance imaging, but with no signs of pathological F- FDG accumulation. The patient died 4 months later, and we found no signs of LCH on autopsy. Our case highlights the need for further studies regarding the role of F-FDG PET/CT in the assessment of treatment response in patients with LCH.
Langerhans Cell Histiocytosis, 18F-FDG PET/CT
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Podaci o izdanju
2015 Dec ; 40(12 (40(12))
2015.
981-982
objavljeno
0363-9762
1536-0229
10.1097/RLU.0000000000000994
Povezanost rada
Kliničke medicinske znanosti