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Pregled bibliografske jedinice broj: 1074900

Sex-Related Differences in Dilated Cardiomyopathy with a Focus on Cardiac Dysfunction in Oncology


D’Amario, Domenico; Camilli, Massimiliano; Migliaro, Stefano; Canonico, Francesco; Galli, Mattia; Arcudi, Alessandra; Montone, Rocco Antonio; Borovac, Josip Anđelo; Crea, Filippo; Savarese, Gianluigi
Sex-Related Differences in Dilated Cardiomyopathy with a Focus on Cardiac Dysfunction in Oncology // Current Cardiology Reports, 22 (2020), 10; 102, 11 doi:10.1007/s11886-020-01377-z (međunarodna recenzija, pregledni rad, znanstveni)


CROSBI ID: 1074900 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Sex-Related Differences in Dilated Cardiomyopathy with a Focus on Cardiac Dysfunction in Oncology

Autori
D’Amario, Domenico ; Camilli, Massimiliano ; Migliaro, Stefano ; Canonico, Francesco ; Galli, Mattia ; Arcudi, Alessandra ; Montone, Rocco Antonio ; Borovac, Josip Anđelo ; Crea, Filippo ; Savarese, Gianluigi

Izvornik
Current Cardiology Reports (1523-3782) 22 (2020), 10; 102, 11

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
Cardio-oncology ; Dilated cardiomyopathy ; Heart failure ; Sex difference

Sažetak
Purpose of review: The aim of this report is to describe the main aspects of sex-related differences in non-ischemic dilated cardiomyopathies (DCM), focusing on chemotherapy-induced heart failure (HF) and investigating the possible therapeutic implications and clinical management applications in the era of personalized medicine. Recent findings: In cardio-oncology, molecular and multimodality imaging studies confirm that sex differences do exist, affecting the therapeutic cardioprotective strategies and, therefore, the long-term outcomes. Interestingly, compelling evidences suggest that sex-specific characteristics in drug toxicity might predict differences in the therapeutic response, most likely due to the tangled interplay between cancer and HF, which probably share common underlying mechanisms. Cardiovascular diseases show many sex-related differences in prevalence, etiology, phenotype expression, and outcomes. Complex molecular mechanisms underlie this diverse pathological manifestations, from sex-determined differential gene expression to sex hormone interaction with their receptors in the heart. Non-ischemic DCM is an umbrella definition that incorporates several etiologies, including chemotherapy-induced cardiomyopathies. The role of sex as a risk factor for cardiotoxicity is poorly explored. However, understanding the various features of disease manifestation and outcomes is of paramount importance for a prompt and tailored evaluation.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Split,
Sveučilište u Splitu

Profili:

Avatar Url JOSIP ANĐELO BOROVAC (autor)

Citiraj ovu publikaciju

D’Amario, Domenico; Camilli, Massimiliano; Migliaro, Stefano; Canonico, Francesco; Galli, Mattia; Arcudi, Alessandra; Montone, Rocco Antonio; Borovac, Josip Anđelo; Crea, Filippo; Savarese, Gianluigi
Sex-Related Differences in Dilated Cardiomyopathy with a Focus on Cardiac Dysfunction in Oncology // Current Cardiology Reports, 22 (2020), 10; 102, 11 doi:10.1007/s11886-020-01377-z (međunarodna recenzija, pregledni rad, znanstveni)
D’Amario, D., Camilli, M., Migliaro, S., Canonico, F., Galli, M., Arcudi, A., Montone, R., Borovac, J., Crea, F. & Savarese, G. (2020) Sex-Related Differences in Dilated Cardiomyopathy with a Focus on Cardiac Dysfunction in Oncology. Current Cardiology Reports, 22 (10), 102, 11 doi:10.1007/s11886-020-01377-z.
@article{article, year = {2020}, pages = {11}, DOI = {10.1007/s11886-020-01377-z}, chapter = {102}, keywords = {Cardio-oncology, Dilated cardiomyopathy, Heart failure, Sex difference}, journal = {Current Cardiology Reports}, doi = {10.1007/s11886-020-01377-z}, volume = {22}, number = {10}, issn = {1523-3782}, title = {Sex-Related Differences in Dilated Cardiomyopathy with a Focus on Cardiac Dysfunction in Oncology}, keyword = {Cardio-oncology, Dilated cardiomyopathy, Heart failure, Sex difference}, chapternumber = {102} }
@article{article, year = {2020}, pages = {11}, DOI = {10.1007/s11886-020-01377-z}, chapter = {102}, keywords = {Cardio-oncology, Dilated cardiomyopathy, Heart failure, Sex difference}, journal = {Current Cardiology Reports}, doi = {10.1007/s11886-020-01377-z}, volume = {22}, number = {10}, issn = {1523-3782}, title = {Sex-Related Differences in Dilated Cardiomyopathy with a Focus on Cardiac Dysfunction in Oncology}, keyword = {Cardio-oncology, Dilated cardiomyopathy, Heart failure, Sex difference}, chapternumber = {102} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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