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Pregled bibliografske jedinice broj: 1073093

UPLC-MS/MS Phytochemical Analysis of Two Croatian Cistus Species and Their Biological Activity


Carev, Ivana; Maravić, Ana; Ilić, Nada; Čikeš Čulić, Vedrana; Politeo, Olivera; Zorić, Zoran; Radan, Mila
UPLC-MS/MS Phytochemical Analysis of Two Croatian Cistus Species and Their Biological Activity // Life, 10 (2020), 7; 112-125 doi:10.3390/life10070112 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1073093 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
UPLC-MS/MS Phytochemical Analysis of Two Croatian Cistus Species and Their Biological Activity

Autori
Carev, Ivana ; Maravić, Ana ; Ilić, Nada ; Čikeš Čulić, Vedrana ; Politeo, Olivera ; Zorić, Zoran ; Radan, Mila

Izvornik
Life (2075-1729) 10 (2020), 7; 112-125

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
antimicrobial ; antioxidant ; antiproliferative ; Cistus ; flavonoid ; UPLC-MS/MS

Sažetak
Aqueous extracts of two Cistus species wild growing in Croatia—Cistus creticus (CC) and Cistus salviifolius (CS)—have been assessed with UPLC-MS/MS, showing 43 different phytochemicals, with flavonol glycosides: myricetin-3-hexoside and myricetin-rhamnoside, predominate ones in CC and myricetin-3-hexoside in CS. Antioxidant potential tested with the FRAP method showed no difference between CS and CC aqueous extracts, while higher phenolic content of CC comparing to CS, determined with a Folin–Cicolateu reagent correlated to its higher antioxidant capacity observed by the DPPH method. Both extracts were assessed for antimicrobial activity, using disc-diffusion and broth microdilution assays, targeting the opportunistic pathogens, associated with food poisoning, urinary, respiratory tract, blood stream and wound infections in humans. Antimicrobial assays revealed that fungi were in general more sensitive to both Cistus aqueous extracts, comparing to the bacteria where two extracts showed very similar activity. The most potent activity was observed against A. baumannii for both extracts. The extracts were tested on human lung cancer (A549) cell line using the MTT assay, showing very similar antiproliferative activity. After 72 h treatment with CC and CS aqueous extracts in concentration of 0.5 g/L, the viability of the cells were 37% and 50% respectively, compared to non-treated cells.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Prehrambena tehnologija



POVEZANOST RADA


Projekti:
HRZZ-IP-2014-09-6897 - Istraživanje bioaktivnih spojeva iz dalmatinskog bilja: njihov antioksidacijski karakter i utjecaj na enzimsku inhibiciju i zdravlje (BioActCom) (Miloš, Mladen, HRZZ - 2014-09) ( POIROT)

Ustanove:
Kemijsko-tehnološki fakultet, Split,
Prehrambeno-biotehnološki fakultet, Zagreb,
Prirodoslovno-matematički fakultet, Split,
Medicinski fakultet, Split

Citiraj ovu publikaciju

Carev, Ivana; Maravić, Ana; Ilić, Nada; Čikeš Čulić, Vedrana; Politeo, Olivera; Zorić, Zoran; Radan, Mila
UPLC-MS/MS Phytochemical Analysis of Two Croatian Cistus Species and Their Biological Activity // Life, 10 (2020), 7; 112-125 doi:10.3390/life10070112 (međunarodna recenzija, članak, znanstveni)
Carev, I., Maravić, A., Ilić, N., Čikeš Čulić, V., Politeo, O., Zorić, Z. & Radan, M. (2020) UPLC-MS/MS Phytochemical Analysis of Two Croatian Cistus Species and Their Biological Activity. Life, 10 (7), 112-125 doi:10.3390/life10070112.
@article{article, year = {2020}, pages = {112-125}, DOI = {10.3390/life10070112}, keywords = {antimicrobial, antioxidant, antiproliferative, Cistus, flavonoid, UPLC-MS/MS}, journal = {Life}, doi = {10.3390/life10070112}, volume = {10}, number = {7}, issn = {2075-1729}, title = {UPLC-MS/MS Phytochemical Analysis of Two Croatian Cistus Species and Their Biological Activity}, keyword = {antimicrobial, antioxidant, antiproliferative, Cistus, flavonoid, UPLC-MS/MS} }
@article{article, year = {2020}, pages = {112-125}, DOI = {10.3390/life10070112}, keywords = {antimicrobial, antioxidant, antiproliferative, Cistus, flavonoid, UPLC-MS/MS}, journal = {Life}, doi = {10.3390/life10070112}, volume = {10}, number = {7}, issn = {2075-1729}, title = {UPLC-MS/MS Phytochemical Analysis of Two Croatian Cistus Species and Their Biological Activity}, keyword = {antimicrobial, antioxidant, antiproliferative, Cistus, flavonoid, UPLC-MS/MS} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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