engleski

Short-Term Safety and Efficacy of Human GH Replacement Therapy in 595 Adults with GH Deficiency: A Comparison of Two Dosage Algorithms

The aim of GH replacement therapy in GH-deficient adults is to optimize response with minimum indicence of adverse reactions, but optimal therapy regimens are still to be established. This two-arm parellel study examined effects of two GH dose algorithms in adults with GH deficiency of adult or childhood onset. The lower starting dose with dose titration appeared more favorable, but differences in response between genders and onset of GH deficiency need to be taken into account when setting an individual dose regimen.

growth hormone (GH); GH replacement therapy; GH deficient adults

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