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Pregled bibliografske jedinice broj: 107100

Immunoregulatory properties of deciduas macrophages


Sedlmayr, Peter; Ćupurdija, Kristijan; Azzola, Dagmar; Dohr, Gottfried; Wintersteiger, Reinhold; Morales, Pedro; Petrof, Margaret G.; Hunt, Joan S.; Gratchev, Alexei; Goerdt, Sergij
Immunoregulatory properties of deciduas macrophages // American journal of reproductive immunology, 48 (2002), 3; 142-142 (podatak o recenziji nije dostupan, kongresno priopcenje, znanstveni)


Naslov
Immunoregulatory properties of deciduas macrophages

Autori
Sedlmayr, Peter ; Ćupurdija, Kristijan ; Azzola, Dagmar ; Dohr, Gottfried ; Wintersteiger, Reinhold ; Morales, Pedro ; Petrof, Margaret G. ; Hunt, Joan S. ; Gratchev, Alexei ; Goerdt, Sergij

Izvornik
American journal of reproductive immunology (1046-7408) 48 (2002), 3; 142-142

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kongresno priopcenje, znanstveni

Sažetak
About 15-20 % of bone marrow derived cells in the endometrium and the decidua are CD14-positive macrophages coexpressing the scavenger receptor CD163. The costimulatory molecule CD86 (B7-2) but not CD80 (B7-1) is found expressed on first trimester and term decidua macrophages (D-Mph). The number of D-Mph increases at the implantation site in the basal decidua, where they are in contact with the HLA-Gpositive invading extravillous cytotrophoblast. As DMph express the inhibitory receptors CD85d (ILT4, LIR-2) and CD85e (ILT2, LIR-1), they are potentially susceptible to inhibition by class Ia and class Ib molecules. D-Mph may have specific functions relating to successful pregnancy, and phenotypic and functional properties may differ between early and term pregnancy. A number of data make their molecular repertoire comparable to those of alternatively activated macrophages which are immunosuppressive. For instance, first trimester decidua macrophages express IL-10 and the MS-1 high molecular weight antigen on the cell surface fibronectin and F XIIIa are detectable. Functional data are required to complement these studies.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

Napomena
8th Congress of the Alps Adria Society for Immunology of Reproduction September 7-10, 2002. ; Udo Markert (Ed.) ; Weimar, Germany Conference venue: 'neue weimarhalle': www.conventus.de/aasir



POVEZANOST RADA


Projekt / tema
0062029

Ustanove
Medicinski fakultet, Rijeka

Profili:

Avatar Url Kristijan Ćupurdija (autor)

Citiraj ovu publikaciju

Sedlmayr, Peter; Ćupurdija, Kristijan; Azzola, Dagmar; Dohr, Gottfried; Wintersteiger, Reinhold; Morales, Pedro; Petrof, Margaret G.; Hunt, Joan S.; Gratchev, Alexei; Goerdt, Sergij
Immunoregulatory properties of deciduas macrophages // American journal of reproductive immunology, 48 (2002), 3; 142-142 (podatak o recenziji nije dostupan, kongresno priopcenje, znanstveni)
Sedlmayr, P., Ćupurdija, K., Azzola, D., Dohr, G., Wintersteiger, R., Morales, P., Petrof, M., Hunt, J., Gratchev, A. & Goerdt, S. (2002) Immunoregulatory properties of deciduas macrophages. American journal of reproductive immunology, 48 (3), 142-142.
@article{article, year = {2002}, pages = {142-142}, keywords = {}, journal = {American journal of reproductive immunology}, volume = {48}, number = {3}, issn = {1046-7408}, title = {Immunoregulatory properties of deciduas macrophages}, keyword = {} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
  • Scopus
  • MEDLINE


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  • Biological Abstracts
  • Chemical Abstracts
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  • Index Medicus