Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1067189

Sarcopenia among patients after allogeneic hematopoietic stem cell transplantation and the impact of chronic graft versus host disease


Ljubas Kelečić, Dina; Lelas, Antonela; Karas, Irena; Desnica, Lana; Vukić, Tamara; Sabol, Ivan; Vranešić Bender, Darija; Serventi Seiwerth, Ranka; Perić, Zinaida; Duraković, Nadira et al.
Sarcopenia among patients after allogeneic hematopoietic stem cell transplantation and the impact of chronic graft versus host disease // Journal of cancer research and clinical oncology, 146 (2020), 2967-2978 doi:10.1007/s00432-020-03280-0 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1067189 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Sarcopenia among patients after allogeneic hematopoietic stem cell transplantation and the impact of chronic graft versus host disease

Autori
Ljubas Kelečić, Dina ; Lelas, Antonela ; Karas, Irena ; Desnica, Lana ; Vukić, Tamara ; Sabol, Ivan ; Vranešić Bender, Darija ; Serventi Seiwerth, Ranka ; Perić, Zinaida ; Duraković, Nadira ; Vitali Čepo, Dubravka ; Vrhovac, Radovan ; Nemet, Damir ; Pavletic, Steven ; Pulanić, Dražen ; Krznarić, Željko

Izvornik
Journal of cancer research and clinical oncology (0171-5216) 146 (2020); 2967-2978

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Sarcopenia ; Allo-HSCT ; cGVHD ; Malnutrition ; Hand-grip strength ; Vitamin D

Sažetak
Purpose This study investigated the frequency and characteristics of sarcopenia among patients after allogeneic hematopoietic stem cell transplantation (allo-HSCT) with a specific focus on the chronic graft-versus-host disease (cGVHD) population and its association with malnutrition, vitamin D and clinical characteristics. Methods We assessed sarcopenia, vitamin D levels, and nutritional status in 73 patients who underwent allo-HSCT, of which 45 were diagnosed with cGVHD. Sarcopenia was diagnosed according to the European Working Group on Sarcopenia in Older People (EWGSOP) criteria. Results Sarcopenia was diagnosed in 19.2% of patients after allo- HSCT with statistically no significant difference between cGVHD and non- cGVHD patients. The risk factor for sarcopenia was the male gender. Sarcopenia in allo-HSCT patients correlated strongly with malnutrition and with current corticosteroid treatment (p < 0.005). Among cGVHD patients sarcopenia additionally correlated strongly with the number of prior systemic immunosuppressive therapy lines (p < 0.005) and moderately with the intensity of immunosuppression, cGVHD severity global rating assessed by both the health care provider and the patient and joint and fascia cGVHD involvement (p < 0.05). Vitamin D deficiency was found in more than 54.8% of patients, but the correlation to sarcopenia was not found. Conclusion Sarcopenia was found to be common in long term survivors of allo-HSCT independently of the cGVHD diagnosis. Prospective longitudinal studies are needed for a better understanding of factors affecting the development of sarcopenia after allo-HSCT.

Izvorni jezik
Engleski

Znanstvena područja
Farmacija



POVEZANOST RADA


Projekti:
IP-2016-06-8046 - Novi biomarkeri kronične bolesti presatka protiv primatelja (Bio-cGVHD) (Pulanić, Dražen, HRZZ - 2016-06) ( POIROT)

Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb,
Institut "Ruđer Bošković", Zagreb,
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb

Citiraj ovu publikaciju

Ljubas Kelečić, Dina; Lelas, Antonela; Karas, Irena; Desnica, Lana; Vukić, Tamara; Sabol, Ivan; Vranešić Bender, Darija; Serventi Seiwerth, Ranka; Perić, Zinaida; Duraković, Nadira et al.
Sarcopenia among patients after allogeneic hematopoietic stem cell transplantation and the impact of chronic graft versus host disease // Journal of cancer research and clinical oncology, 146 (2020), 2967-2978 doi:10.1007/s00432-020-03280-0 (međunarodna recenzija, članak, znanstveni)
Ljubas Kelečić, D., Lelas, A., Karas, I., Desnica, L., Vukić, T., Sabol, I., Vranešić Bender, D., Serventi Seiwerth, R., Perić, Z. & Duraković, N. (2020) Sarcopenia among patients after allogeneic hematopoietic stem cell transplantation and the impact of chronic graft versus host disease. Journal of cancer research and clinical oncology, 146, 2967-2978 doi:10.1007/s00432-020-03280-0.
@article{article, year = {2020}, pages = {2967-2978}, DOI = {10.1007/s00432-020-03280-0}, keywords = {Sarcopenia, Allo-HSCT, cGVHD, Malnutrition, Hand-grip strength, Vitamin D}, journal = {Journal of cancer research and clinical oncology}, doi = {10.1007/s00432-020-03280-0}, volume = {146}, issn = {0171-5216}, title = {Sarcopenia among patients after allogeneic hematopoietic stem cell transplantation and the impact of chronic graft versus host disease}, keyword = {Sarcopenia, Allo-HSCT, cGVHD, Malnutrition, Hand-grip strength, Vitamin D} }
@article{article, year = {2020}, pages = {2967-2978}, DOI = {10.1007/s00432-020-03280-0}, keywords = {Sarcopenia, Allo-HSCT, cGVHD, Malnutrition, Hand-grip strength, Vitamin D}, journal = {Journal of cancer research and clinical oncology}, doi = {10.1007/s00432-020-03280-0}, volume = {146}, issn = {0171-5216}, title = {Sarcopenia among patients after allogeneic hematopoietic stem cell transplantation and the impact of chronic graft versus host disease}, keyword = {Sarcopenia, Allo-HSCT, cGVHD, Malnutrition, Hand-grip strength, Vitamin D} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font