engleski

FINE NEEDLE ASPIRATION DIAGNOSIS OF CAROTID BODY TUMOR-A CASE REPORT

Objectives: Carotid body tumors (CBT) are neuroendocrine neoplasias that belong to the group of extraadrenal paragangliomas of head and neck. They are rare neoplasms that represent less than 0, 5% of head and neck tumors. We report a case of 50-year old man with swelling anterior to the sternocleidomastoid muscle with no other clinical symptoms. Materials and Methods: Ultrasound guided fine needle aspiration (FNA) samples were performed and May-Grunvald- Giemsa (MGG) smears were prepared. Solid tissue was prepared in cell block and was obtained with Hemalaun-eosin (HE) and immunohistochemical staining with SMA, EMSA desmin, chromogranin, synaptophysin, NSE and S-100. Results: A 50-year old non–hypertensive man, without syncope attack presented with a mass 3 cm in size, which had slowly been increasing in size over past 3 years. The computed tomography (CT) scan has confirmed carotid body tumor. Tumor was located anterior to the sternocleidomastoid muscle. Ultrasound guided FNA was done. The cytological slides showed clusters of epithelial cells partially in acinar pattern. Cells were round, dark nucleated with indistinct, pale syncytial cytoplasm in hemorrhagic background. In considering the localization and findings of other imaging technics a diagnose of carotid body tumor was concluded. Immunohistochemical stains demonstrated chromogranin, synaptophysin, NSE and S-100 positivity and the pathologist reported paraganglioma. Conclusion: As in preoperative diagnostic processing of suspected carotid body tumor it is not recommended to do the open biopsy due to possible hemorrhage, consequently FNA remains the reliable tissue diagnostic method combined with data and other ancillary imaging technics.

carotid body ; FNA ; paraganglioma

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