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Pregled bibliografske jedinice broj: 1064745

Association of bacterial load in drinking water and allergic diseases in childhood


Turkalj, Mirjana; Drkulec, Vlado; Haider, Sadia; Plavec, Davor; Banić, Ivana; Malev, Olga; Erceg, Damir; Woodcock, Ashley; Nogalo, Boro; Čustović, Adnan
Association of bacterial load in drinking water and allergic diseases in childhood // Clinical and experimental allergy, 50 (2020), 733-740 doi:10.1111/cea.13605 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1064745 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Association of bacterial load in drinking water and allergic diseases in childhood
(Association of bacterial load in drinking water and allergic diseases in childhood)

Autori
Turkalj, Mirjana ; Drkulec, Vlado ; Haider, Sadia ; Plavec, Davor ; Banić, Ivana ; Malev, Olga ; Erceg, Damir ; Woodcock, Ashley ; Nogalo, Boro ; Čustović, Adnan

Izvornik
Clinical and experimental allergy (0954-7894) 50 (2020); 733-740

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
atopy ; bacterial load ; children ; drinking water ; microbiota ; well water

Sažetak
Background: Treatment of drinking water may decrease microbial exposure. Objective: To investigate whether bacterial load in drinking water is associated with altered risk of allergic diseases. Methods: We recruited 1, 110 school children aged 6-16 years between 2011 and 2013 in Požega-Slavonia County in Croatia, where we capitalized on a natural experiment where by individuals receive drinking water through public mains supply or individual wells. We obtained data on microbial content of drinking water for all participants ; 585 children were randomly selected for more detailed assessments, including skin prick testing. Since water supply was highly correlated with rural residence, we compared clinical outcomes across four groups (Rural/Individual, Rural/Public, Urban/Individual and Urban/Public). For each child, we derived quantitative index of microbial exposure (bacterial load in the drinking water measured during the child's first year of life). Results: Cumulative bacterial load in drinking water was higher (median [IQR]: 6390 [4190-9550] vs 0 [0-0] ; P < .0001), and lifetime prevalence of allergic diseases was significantly lower among children with individual supply (5.5% vs 2.3%, P = .01 ; 14.4% vs 6.7%, P < .001 ; 25.2% vs 15.1%, P < .001 ; asthma, atopic dermatitis [AD] and rhinitis, respectively). Compared with the reference group (Urban/Public), there was a significant reduction in the risk of ever asthma, AD and rhinitis amongst rural children with individual supply: OR [95% CI]: 0.14 [0.03, 0.67], P = .013 ; 0.20 [0.09, 0.43], P < .001 ; 0.17 [0.10, 0.32], P < .001. Protection was also observed in the Rural/Public group, but the effect was consistently highest among Rural/Individual children. In the quantitative analysis, the risk of allergic diseases decreased significantly with increasing bacterial load in drinking water in the first year of life (0.79 [0.70, 0.88], P < .001 ; 0.90 [0.83, 0.99], P = .025 ; 0.80 [0.74, 0.86], P < .001 ; current wheeze, AD and rhinitis). Conclusions and Clinical Relevance: High commensal bacterial content in drinking water may protect against allergic diseases.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Prirodoslovno-matematički fakultet, Zagreb,
Medicinski fakultet, Osijek,
Dječja bolnica Srebrnjak,
Opća županijska bolnica Požega,
Hrvatsko katoličko sveučilište, Zagreb,
Fakultet za dentalnu medicinu i zdravstvo, Osijek

Profili:

Avatar Url Vlado Drkulec (autor)

Avatar Url Davor Plavec (autor)

Avatar Url Olga Malev (autor)

Avatar Url Boro Nogalo (autor)

Avatar Url Damir Erceg (autor)

Avatar Url Mirjana Turkalj (autor)

Poveznice na cjeloviti tekst rada:

doi onlinelibrary.wiley.com

Citiraj ovu publikaciju:

Turkalj, Mirjana; Drkulec, Vlado; Haider, Sadia; Plavec, Davor; Banić, Ivana; Malev, Olga; Erceg, Damir; Woodcock, Ashley; Nogalo, Boro; Čustović, Adnan
Association of bacterial load in drinking water and allergic diseases in childhood // Clinical and experimental allergy, 50 (2020), 733-740 doi:10.1111/cea.13605 (međunarodna recenzija, članak, znanstveni)
Turkalj, M., Drkulec, V., Haider, S., Plavec, D., Banić, I., Malev, O., Erceg, D., Woodcock, A., Nogalo, B. & Čustović, A. (2020) Association of bacterial load in drinking water and allergic diseases in childhood. Clinical and experimental allergy, 50, 733-740 doi:10.1111/cea.13605.
@article{article, author = {Turkalj, Mirjana and Drkulec, Vlado and Haider, Sadia and Plavec, Davor and Bani\'{c}, Ivana and Malev, Olga and Erceg, Damir and Woodcock, Ashley and Nogalo, Boro and \v{C}ustovi\'{c}, Adnan}, year = {2020}, pages = {733-740}, DOI = {10.1111/cea.13605}, keywords = {atopy, bacterial load, children, drinking water, microbiota, well water}, journal = {Clinical and experimental allergy}, doi = {10.1111/cea.13605}, volume = {50}, issn = {0954-7894}, title = {Association of bacterial load in drinking water and allergic diseases in childhood}, keyword = {atopy, bacterial load, children, drinking water, microbiota, well water} }
@article{article, author = {Turkalj, Mirjana and Drkulec, Vlado and Haider, Sadia and Plavec, Davor and Bani\'{c}, Ivana and Malev, Olga and Erceg, Damir and Woodcock, Ashley and Nogalo, Boro and \v{C}ustovi\'{c}, Adnan}, year = {2020}, pages = {733-740}, DOI = {10.1111/cea.13605}, keywords = {atopy, bacterial load, children, drinking water, microbiota, well water}, journal = {Clinical and experimental allergy}, doi = {10.1111/cea.13605}, volume = {50}, issn = {0954-7894}, title = {Association of bacterial load in drinking water and allergic diseases in childhood}, keyword = {atopy, bacterial load, children, drinking water, microbiota, well water} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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