engleski

Effect of microencapsulated granulas contained in the natural extracts on postsurgical wound healing

Background The innovative complex technology of encapsulation of the natural extracts allows the products to be more efficient in surgical wound healing due to penetration of the microcapsules in the soft tissues. Aims The aim of the randomized controlled trial was to evaluate the effectiveness of microencapsulated natural extracts contained in the gel on wound healing process after oral surgical procedures.Methods The study included 95 patients with indications for endodontic surgery: third molar surgical extraction or dental implants placement. The patients were randomly divided in two groups based on the postsurgical protocol on treating the wound after surgery: A/: Subgroup 1: GinGinat group used a gel composed of different natural products (GinGinat gel, LoB Foundation, Paris, France) for treating the surgical area ; B/ Subgroup 2: Standard protocol used saline solution for treating the wound after surgery. At the seven day follow upallpatients were asked to rate their experience and satisfaction on the recovery process after surgery based on a questionnaire. They were observed and evaluated for satisfaction with the recovery process based on using Likert-type scale. Results The results showed a statistically significant difference in the postoperative recovery period between the GinGinat and standard group (p<0.001) based on a therapist’s evaluation. The GinGinat group was rated with the higher clinical score compared to the standard group (p<0.001). There was a statistically significant difference in the recovery postoperative period between the GinGinat and standard group as rated based on the results of a patient’s questionnaire (p<0.001). Conclusion The results showed clinical improvement and better postsurgical healing of the wounds as well as the stronger analgesic effect after the application of microencapsulated granulas which are contained in the natural extracts as opposed to the standard postsurgical protocol.

wound healing ; microencapsulation ; essential oil ; plant extracts ; oral surgery

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