engleski

EFFICACY OF LOCALLY INFILTRATED LEVOBUPIVACAINE AND LIDOCAINE FOR POSTOPERATIVE ANALGESIA FOLLOWING NASAL SURGERY IN THE AMBULATORY SETTING

Background and Aims: We compared the use of preincisional 2% lidocaine with epinephrine (LA) and levobupivacaine 0.25% plain (LB) for postoperative analgesia in patients undergoing nasal surgery. Methods: Sixty patients were randomly assigned to receive preincisional local infiltration under general anesthesia. Group LB received levobupivacaine 0, 25% , and group LA epinephrine + 2% lidocaine. Visual analog scale values 30 min and 1, 3, 6 h postoperatively and the need for rescue analgesic treatment in the first 24h of all patients was recorded. Results: At 30 min under 1, 3, 6 h postoperatively, visual analog scale values were lower in group LB than in group LA (P<0.0001, P=0.002, P=0.023, P<0.301, respectively). The analgesic requirement was significantly lower in group LB when compared with that in group LA (P=0.038). Conclusions: We conclude that postoperative analgesia in nasal surgery with local infiltration of levobupivacaine as an adjunct to general anesthesia, was significantly more potent and longer lasting than that achieved by lidocaine + epinephrine. Conventional non- steroidal anti-inflammatory drugs in combination with paracetamol, administrated in time to provide sufficient analgesia in the early recovery phase are optimal in addition, weak opioids are recommended for moderate pain and strong opioids for severe pain, on request.

preincisional ; lidocaine ; epinephrine ; levobupivacaine ; postoperative analgesia ; nasal surgery

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