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Pregled bibliografske jedinice broj: 1059412

The association between vegetation size and surgical treatment on 6-month mortality in left-sided infective endocarditis


Fosbøl, Emil L; Park, Lawrence P; Chu, Vivian H; Athan, Eugene; Delahaye, Francois; Freiberger, Tomas; Lamas, Cristiane; Miro, Jose M; Strahilevitz, Jacob; Tribouilloy, Christophe et al.
The association between vegetation size and surgical treatment on 6-month mortality in left-sided infective endocarditis // European Heart Journal, 40 (2019), 27; 2243-2251 doi:10.1093/eurheartj/ehz204 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1059412 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
The association between vegetation size and surgical treatment on 6-month mortality in left-sided infective endocarditis

Autori
Fosbøl, Emil L ; Park, Lawrence P ; Chu, Vivian H ; Athan, Eugene ; Delahaye, Francois ; Freiberger, Tomas ; Lamas, Cristiane ; Miro, Jose M ; Strahilevitz, Jacob ; Tribouilloy, Christophe ; Durante-Mangoni, Emanuele ; Pericas, Juan M ; Fernández-Hidalgo, Nuria ; Nacinovich, Francisco ; Rizk, Hussein ; Barsic, Bruno ; Giannitsioti, Efthymia ; Hurley, John P ; Hannan, Margaret M ; Wang, Andrew ; ICE-PLUS Investigators

Izvornik
European Heart Journal (0195-668X) 40 (2019), 27; 2243-2251

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Antibiotics ; Infective endocarditis ; Outcomes ; Surgery ; Vegetation size

Sažetak
AIMS: In left-sided infective endocarditis (IE), a large vegetation >10 mm is associated with higher mortality, yet it is unknown whether surgery during the acute phase opposed to medical therapy is associated with improved survival. We assessed the association between surgery and 6-month mortality as related to vegetation size. METHODS AND RESULTS: Patients with definite, left-sided IE (2008-2012) from The International Collaboration on Endocarditis prospective, multinational registry were included. We compared clinical characteristics and 6-month mortality (by Cox regression with inverse propensity of treatment weighting) between patients with vegetation size ≤10 mm vs. >10 mm in maximum length by surgical treatment strategy. A total of 1006 patients with left sided IE were included ; 422 with a vegetation size ≤10 mm (median age 66.0 years, 33% women) and 584 (median age 58.4 years, 34% women) patients with a large vegetation >10 mm. Operative risk by STS-IE score was similar between groups. Embolic events occurred in 28.4% vs. 44.3% (P < 0.001), respectively. Patients with a vegetation >10 mm was associated with higher 6-month mortality (25.1% vs. 19.4% for small vegetation, P = 0.035). However, after propensity adjustment, the association with higher mortality persisted only in patients with a large vegetation >10 mm vs. ≤10 mm: hazard ratio (HR) 1.55 (1.27-1.90) ; but only in patients with large vegetation managed medically [HR 1.86 (1.48-2.34)] rather than surgically [HR 1.01 (0.69-1.49)]. CONCLUSION: Left-sided IE with vegetation size >10 mm was associated with an increased mortality at 6 months in this observational study but was dependent on treatment strategy. For patients with large vegetation undergoing surgical treatment, survival was similar to patients with smaller vegetation size.

Izvorni jezik
Engleski



POVEZANOST RADA


Ustanove:
Klinika za infektivne bolesti "Dr Fran Mihaljević",
Fakultet za dentalnu medicinu i zdravstvo, Osijek

Profili:

Avatar Url Bruno Baršić (autor)

Avatar Url Suzana Bukovski (autor)

Poveznice na cjeloviti tekst rada:

doi

Citiraj ovu publikaciju:

Fosbøl, Emil L; Park, Lawrence P; Chu, Vivian H; Athan, Eugene; Delahaye, Francois; Freiberger, Tomas; Lamas, Cristiane; Miro, Jose M; Strahilevitz, Jacob; Tribouilloy, Christophe et al.
The association between vegetation size and surgical treatment on 6-month mortality in left-sided infective endocarditis // European Heart Journal, 40 (2019), 27; 2243-2251 doi:10.1093/eurheartj/ehz204 (međunarodna recenzija, članak, znanstveni)
Fosbøl, E., Park, L., Chu, V., Athan, E., Delahaye, F., Freiberger, T., Lamas, C., Miro, J., Strahilevitz, J. & Tribouilloy, C. (2019) The association between vegetation size and surgical treatment on 6-month mortality in left-sided infective endocarditis. European Heart Journal, 40 (27), 2243-2251 doi:10.1093/eurheartj/ehz204.
@article{article, author = {Fosb\ol, Emil L and Park, Lawrence P and Chu, Vivian H and Athan, Eugene and Delahaye, Francois and Freiberger, Tomas and Lamas, Cristiane and Miro, Jose M and Strahilevitz, Jacob and Tribouilloy, Christophe and Durante-Mangoni, Emanuele and Pericas, Juan M and Fern\'{a}ndez-Hidalgo, Nuria and Nacinovich, Francisco and Rizk, Hussein and Barsic, Bruno and Giannitsioti, Efthymia and Hurley, John P and Hannan, Margaret M and Wang, Andrew}, year = {2019}, pages = {2243-2251}, DOI = {10.1093/eurheartj/ehz204}, keywords = {Antibiotics, Infective endocarditis, Outcomes, Surgery, Vegetation size}, journal = {European Heart Journal}, doi = {10.1093/eurheartj/ehz204}, volume = {40}, number = {27}, issn = {0195-668X}, title = {The association between vegetation size and surgical treatment on 6-month mortality in left-sided infective endocarditis}, keyword = {Antibiotics, Infective endocarditis, Outcomes, Surgery, Vegetation size} }
@article{article, author = {Fosb\ol, Emil L and Park, Lawrence P and Chu, Vivian H and Athan, Eugene and Delahaye, Francois and Freiberger, Tomas and Lamas, Cristiane and Miro, Jose M and Strahilevitz, Jacob and Tribouilloy, Christophe and Durante-Mangoni, Emanuele and Pericas, Juan M and Fern\'{a}ndez-Hidalgo, Nuria and Nacinovich, Francisco and Rizk, Hussein and Barsic, Bruno and Giannitsioti, Efthymia and Hurley, John P and Hannan, Margaret M and Wang, Andrew}, year = {2019}, pages = {2243-2251}, DOI = {10.1093/eurheartj/ehz204}, keywords = {Antibiotics, Infective endocarditis, Outcomes, Surgery, Vegetation size}, journal = {European Heart Journal}, doi = {10.1093/eurheartj/ehz204}, volume = {40}, number = {27}, issn = {0195-668X}, title = {The association between vegetation size and surgical treatment on 6-month mortality in left-sided infective endocarditis}, keyword = {Antibiotics, Infective endocarditis, Outcomes, Surgery, Vegetation size} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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