engleski

Comparison of fluoride ion release from fluoride gel in various solvents

Introduction: High concentration fluoride gels are used for caries prevention and therapy. The aim of this study was to determine the concentration of fluoride ions in various solutions of fluoride gels pertaining to the label amount of fluoride concentration. Materials and methods: Two fluoride gels containing different active ingredients were used in this study. Mirafluor gel with sodium fluoride and Elmex gel with amine fluorides and sodium fluoride. Solvents used in this study were distilled water, redistilled water, tap water, 0.9% sodium chloride solution and the artificial saliva product Axerosta. Pure solvents samples were prepared, as well as one gel solution per each particular solvent. Next, the amount of fluoride ion (F-) was determined by use of ion-selective electrode (ISO 19448:2018 standard). Results: F- ion concentrations in pure solvent samples were negligibly low and could not increase F- ion concentrations in fluoride gels solutions. The differences between F- ion release in various solvents were statistically significant (ANOVA, p < 0.05). The F- ion concentrations measured in both gels’ redistilled water solutions were higher than the label concentration. There was a significant difference in fluoride ion release in every Mirafluor gel solution except between distilled and redistilled water solutions. Fluoride ion release was significantly different in every Elmex gel solution except between distilled and redistilled water solutions and between redistilled water and artificial saliva Axerosta solutions. Conclusions: Amine fluorides do not interact with other ions present in the solution, whereas F- ion release from sodium fluoride alters when other ions are dissolved in the same solution.

fluoride ; fluoride release ; ion-selective electrode

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