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Pregled bibliografske jedinice broj: 1058973

Comparation of inflammatory bowel disease therapy with an emphasis on immune therapy; results of research study of inflammatory bowel disease in the Osijek-baranja county 2000-2014


Žulj, Marinko; Steiner Kristina; Steiner Srdarević Sabina; Tomić Matej; Vezmar Ana Marija; Vuković Mladen; , Vranjić Petar; Boban Marko; Tadžić Refmir; Matijević Marko et al.
Comparation of inflammatory bowel disease therapy with an emphasis on immune therapy; results of research study of inflammatory bowel disease in the Osijek-baranja county 2000-2014 // 11th ISABS Conference on Forensic and Anthropologic Genetics and Mayo Clinic Lectures in Individualized Medicine Abstract Book
Split, Hrvatska, 2019. str. 202-202 (poster, međunarodna recenzija, sažetak, ostalo)


CROSBI ID: 1058973 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Comparation of inflammatory bowel disease therapy with an emphasis on immune therapy; results of research study of inflammatory bowel disease in the Osijek-baranja county 2000-2014

Autori
Žulj, Marinko ; Steiner Kristina ; Steiner Srdarević Sabina ; Tomić Matej ; Vezmar Ana Marija ; Vuković Mladen ; , Vranjić Petar ; Boban Marko ; Tadžić Refmir ; Matijević Marko ; Ivanišević Zrinka ; Štambuk Krešimir ; Šesto Igor ; Szavits-Nossan Janko ; Volarić Nikola ; Kralik Kristina ; Krstačić Antonija ; Krstačić Goran ; Steiner Robert ; Mirat Jure ; Včev Aleksandar

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
11th ISABS Conference on Forensic and Anthropologic Genetics and Mayo Clinic Lectures in Individualized Medicine Abstract Book / - , 2019, 202-202

Skup
11th ISABS Conference on Forensic and Anthropologic Genetics and Mayo Clinic Lectures in Individualized Medicine

Mjesto i datum
Split, Hrvatska, 17-22.06.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
: inflammatory bowel disease, antibiotics, corticosteroids, immunosupressants, biological agents

Sažetak
BACKGROUND: One of the significant health issues in modern era are ulcerative colitis (UC) and Crohn's disease (CD). Beneath clinical manifestation of those inflammatory bowel diseases (IBDs) lays chronic inflammation of gastrointestinal wall, mediated by the release of interleukins, cytokines and TNF. Drugs used in treatment are antibiotics, corticosteroids, immunomodulators and biological agents. Aim of this study was to compare usage of immunomodualting drugs vs. antibiotics and corticosteroids in treatment of IBDs during the time. Results in this study are part of results of the doctoral dissertation by M. Žulj, MD. MATERIAL AND METHODS:This study is based on medical documentation of IBD patients treated at KBC Osijek and OB Našice in the period of 2000-2014. In total of 78 patients, 51 was diagnosed with UC and 27 with CD. This study is a part of the university project "Povezanost polimorfizama jednog nukleotida u NOD 2 i MDR 1 genima s nastankom upalnih bolesti crijeva" VIF 2016-MEFOS 16 conducted at the University J.J.Strossmayer led by prof.dr.sc. A.Včev. RESULTS: At the beginning of treatment there was a statistical significant difference in usage of antibiotics between groups with UC and CD (32 UC, 10 CD, p=0, 03 χ2test), immunosupressants (11 UC, 15 CD, p=0, 001 χ2test) and biological agents (7 UC, 9 CD, p=0, 04 χ2test) while there was no statistical significant difference in usage of corticosteroids (36 UC, 21 CD, p=0, 59, χ2test). During this study drugs used in treatment of those patients were modified. Statistical significant differences were found in usage of biological agents (7 UC, 17 CD, p<0, 001, χ2test) while there was no statistical significant difference in usage of antibiotics (3 UC, 1 CD, p>0, 99, χ2test), corticosteroids (13 UC, 3 CD, p=0, 13, χ2test) and immunosupressants (6 UC, 4 CD, p=0, 72, χ2test). CONCLUSION: Although drug groups used in treatment of UC and CD are similar, biological agents are mostly used in CD while corticosteroids are used in UC and CD equally, regardless of time of the treatment. Immunosupressants are mostly used in patients with CD while antibiotics in patients with UC at the beginning of treatment.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove
Medicinski fakultet, Osijek,
Fakultet za dentalnu medicinu i zdravstvo, Osijek

Citiraj ovu publikaciju

Žulj, Marinko; Steiner Kristina; Steiner Srdarević Sabina; Tomić Matej; Vezmar Ana Marija; Vuković Mladen; , Vranjić Petar; Boban Marko; Tadžić Refmir; Matijević Marko et al.
Comparation of inflammatory bowel disease therapy with an emphasis on immune therapy; results of research study of inflammatory bowel disease in the Osijek-baranja county 2000-2014 // 11th ISABS Conference on Forensic and Anthropologic Genetics and Mayo Clinic Lectures in Individualized Medicine Abstract Book
Split, Hrvatska, 2019. str. 202-202 (poster, međunarodna recenzija, sažetak, ostalo)
Žulj, M., Steiner Kristina, Steiner Srdarević Sabina, Tomić Matej, Vezmar Ana Marija, Vuković Mladen, , V., Boban Marko, Tadžić Refmir & Matijević Marko et al. (2019) Comparation of inflammatory bowel disease therapy with an emphasis on immune therapy; results of research study of inflammatory bowel disease in the Osijek-baranja county 2000-2014. U: 11th ISABS Conference on Forensic and Anthropologic Genetics and Mayo Clinic Lectures in Individualized Medicine Abstract Book.
@article{article, year = {2019}, pages = {202-202}, keywords = {: inflammatory bowel disease, antibiotics, corticosteroids, immunosupressants, biological agents}, title = {Comparation of inflammatory bowel disease therapy with an emphasis on immune therapy; results of research study of inflammatory bowel disease in the Osijek-baranja county 2000-2014}, keyword = {: inflammatory bowel disease, antibiotics, corticosteroids, immunosupressants, biological agents}, publisherplace = {Split, Hrvatska} }