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Pregled bibliografske jedinice broj: 1058812

Respiratory and allergic disorders in children with severe and partial immunoglobulin A immunodeficiency


Živković, Jelena; Lipej, Marcel; Banić, Ivana; Bulat Lokas, Sandra; Nogalo, Boro; Lulić Jurjević, Rajka; Turkalj, Mirjana
Respiratory and allergic disorders in children with severe and partial immunoglobulin A immunodeficiency // Scandinavian journal of immunology, 90 (2019), 6; 1058812, 7 doi:10.1111/sji.12828 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1058812 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Respiratory and allergic disorders in children with severe and partial immunoglobulin A immunodeficiency

Autori
Živković, Jelena ; Lipej, Marcel ; Banić, Ivana ; Bulat Lokas, Sandra ; Nogalo, Boro ; Lulić Jurjević, Rajka ; Turkalj, Mirjana

Izvornik
Scandinavian journal of immunology (0300-9475) 90 (2019), 6; 1058812, 7

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
allergic diseases ; lung function ; partial and severe IgA deficiency ; recurrent infections
(allergic diseases ; lung function ; partall and severe IgA deficiency ; recurrent infections)

Sažetak
BACKGROUND: Immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency. Although most people with selective IgAD (sIgAD) are asymptomatic, many patients often suffer from recurrent respiratory infections and different allergic disorders. Our aim was to investigate connection between subtypes of sIgAD and incidence of respiratory and allergic disorders, as well as connection with lung function changes in children. METHODS: Children with IgAD where divided into two groups ; severe IgAD in patients was defined as serum IgA level <7 mg/dL, while partial IgA deficiency diagnosis was made when serum IgA levels was higher than 7 mg/dL but at least two standard deviations (SD) below mean normal concentrations for their age. All patients were evaluated by their clinical and laboratory investigation parameters and compared to control group of children. RESULTS: Group of children with IgAD, severe as well as partial, showed higher prevalence of allergic diseases and total number of infections, compared to controls. There was a statistically significant difference in lung function for peak expiratory flow (PEF), the maximal expiratory flow at 50% of the forced vital capacity (MEF50) and fraction of exhaled nitric oxide (FENO) between group of patients with severe as well as partial IgAD and control group, where children with IgAD showed reduced lung function. CONCLUSIONS: Children with sIgAD are at increased risk for higher number of respiratory infections and developing allergic diseases, resulting in significantly lower pulmonary function which is related with the severity of sIgAD.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Dječja bolnica Srebrnjak,
Fakultet za dentalnu medicinu i zdravstvo, Osijek

Citiraj ovu publikaciju

Živković, Jelena; Lipej, Marcel; Banić, Ivana; Bulat Lokas, Sandra; Nogalo, Boro; Lulić Jurjević, Rajka; Turkalj, Mirjana
Respiratory and allergic disorders in children with severe and partial immunoglobulin A immunodeficiency // Scandinavian journal of immunology, 90 (2019), 6; 1058812, 7 doi:10.1111/sji.12828 (međunarodna recenzija, članak, znanstveni)
Živković, J., Lipej, M., Banić, I., Bulat Lokas, S., Nogalo, B., Lulić Jurjević, R. & Turkalj, M. (2019) Respiratory and allergic disorders in children with severe and partial immunoglobulin A immunodeficiency. Scandinavian journal of immunology, 90 (6), 1058812, 7 doi:10.1111/sji.12828.
@article{article, year = {2019}, pages = {7}, DOI = {10.1111/sji.12828}, chapter = {1058812}, keywords = {allergic diseases, lung function, partial and severe IgA deficiency, recurrent infections}, journal = {Scandinavian journal of immunology}, doi = {10.1111/sji.12828}, volume = {90}, number = {6}, issn = {0300-9475}, title = {Respiratory and allergic disorders in children with severe and partial immunoglobulin A immunodeficiency}, keyword = {allergic diseases, lung function, partial and severe IgA deficiency, recurrent infections}, chapternumber = {1058812} }
@article{article, year = {2019}, pages = {7}, DOI = {10.1111/sji.12828}, chapter = {1058812}, keywords = {allergic diseases, lung function, partall and severe IgA deficiency, recurrent infections}, journal = {Scandinavian journal of immunology}, doi = {10.1111/sji.12828}, volume = {90}, number = {6}, issn = {0300-9475}, title = {Respiratory and allergic disorders in children with severe and partial immunoglobulin A immunodeficiency}, keyword = {allergic diseases, lung function, partall and severe IgA deficiency, recurrent infections}, chapternumber = {1058812} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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