engleski

Paraneoplastic Neurological Syndrome with Demyelinating Polyradiculoneuropathy in Tonsil Cancer patient

Objective: To describe a rare case of a paraneoplastic neurological syndrome associated with tonsillar squamous cell carcinoma. Design: Case report. Patient: A 51-year-old female patient with paraneoplastic neurological disorder characterized by rapid and progressive bilateral facial paresis, diplopia, arm and leg weakness and paresthesia. Interventions: Symptomatic therapy for pain, surgery and radiotherapy for cancer. Main outcome measures: Medical file, radiological imaging, EMNG, immunological findings and surgical report. Results: Patient neurological status drastically improved in early postoperative period (after primary surgical intervention). Only mild right facial paresis persisted upon release from hospital. Patient is scheduled for radiotherapy. Conclusion: This is to our knowledge first case of paraneoplastic neurogical syndrome with demyelinating polyradiculoneuropathy associated with tonsillar carcinoma. In a case of an early staged carcinoma, symptomatic therapy and surgery alleviated or slowed progression of symptoms.

Tonsilar carcinoma, Paraneoplastic neurological syndrome, Facial nerve palsy, Surgery

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