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Pregled bibliografske jedinice broj: 1058318

An association between niacin skin flush response and plasma triglyceride levels in patients with schizophrenia


Nadalin, Sergej; Jonovska, Suzana; Šendula Jengić, Vesna; Buretić-Tomljanović, Alena
An association between niacin skin flush response and plasma triglyceride levels in patients with schizophrenia // Prostaglandins, Leukotrienes and Essential Fatty Acids, 155 (2020), /-/ doi:10.1016/j.plefa.2020.102084 (međunarodna recenzija, članak, znanstveni)


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Naslov
An association between niacin skin flush response and plasma triglyceride levels in patients with schizophrenia

Autori
Nadalin, Sergej ; Jonovska, Suzana ; Šendula Jengić, Vesna ; Buretić-Tomljanović, Alena

Izvornik
Prostaglandins, Leukotrienes and Essential Fatty Acids (0952-3278) 155 (2020); /-/

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Arachidonic acid-signaling ; Niacin skin flush response ; Plasma glucose ; Plasma lipids ; Schizophrenia

Sažetak
The available data suggest that abnormalities of arachidonic acid-related signaling may be of relevance in attenuated niacin-induced flush responses and lipid and glucose metabolism disturbances, which are all common among individuals with schizophrenia. We previously demonstrated attenuated skin flush responses to niacin in patients with schizophrenia. Here we investigated whether these niacin responses might be associated with elevated plasma lipid and glucose concentrations in this patient group. We found that higher plasma triglyceride levels were associated with higher total volumetric niacin response (VNR) values and that the VNR accounted for ~14.2% of the variability in triglyceride levels. Triglyceride levels were significantly higher in patients with a positive niacin skin flush response compared to those with absent niacin skin flushing at the 5-minute interval with niacin concentrations of 0.1 and 0.01 M, and at the 10- and 15-minute intervals with a niacin concentration of 0.001 M.

Izvorni jezik
Engleski



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Rijeka,
Fakultet zdravstvenih studija u Rijeci

Citiraj ovu publikaciju

Nadalin, Sergej; Jonovska, Suzana; Šendula Jengić, Vesna; Buretić-Tomljanović, Alena
An association between niacin skin flush response and plasma triglyceride levels in patients with schizophrenia // Prostaglandins, Leukotrienes and Essential Fatty Acids, 155 (2020), /-/ doi:10.1016/j.plefa.2020.102084 (međunarodna recenzija, članak, znanstveni)
Nadalin, S., Jonovska, S., Šendula Jengić, V. & Buretić-Tomljanović, A. (2020) An association between niacin skin flush response and plasma triglyceride levels in patients with schizophrenia. Prostaglandins, Leukotrienes and Essential Fatty Acids, 155, /-/ doi:10.1016/j.plefa.2020.102084.
@article{article, year = {2020}, pages = {/-/}, DOI = {10.1016/j.plefa.2020.102084}, keywords = {Arachidonic acid-signaling, Niacin skin flush response, Plasma glucose, Plasma lipids, Schizophrenia}, journal = {Prostaglandins, Leukotrienes and Essential Fatty Acids}, doi = {10.1016/j.plefa.2020.102084}, volume = {155}, issn = {0952-3278}, title = {An association between niacin skin flush response and plasma triglyceride levels in patients with schizophrenia}, keyword = {Arachidonic acid-signaling, Niacin skin flush response, Plasma glucose, Plasma lipids, Schizophrenia} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
  • Scopus
  • MEDLINE


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