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Pregled bibliografske jedinice broj: 1058208

BIOMARKERS DETECTED BY THE INFRARED SPECTROSCOPY IN SPENT MEDIA METABOLOMES OF EMBRYO_DERIVED TERATOMAS TREATED WITH VALPROATE IN VIVO


(Croatian Society of Biochemistry and Molecular Biology) Plazibat, Milvija; Katušić-Bojana, AnaHimerleich Perić, Marta; Gamulin, Ozren; Mario Rašić, Vedran Radonić, DĂƌŬŽŠkrabić, Maria Krajačić, Jure Krasić, Nino Sinčić, Gordana JurićͲLekić, Maja Balarin†, Floriana BulićͲ Jakuš Gamulin, Ozren; Rašić, Mario; Radonić, Vedran; , Krajačić, Maria; Krasić, Jure; Sinči, Nino; Jurić- Lekić, Gordana et al.
BIOMARKERS DETECTED BY THE INFRARED SPECTROSCOPY IN SPENT MEDIA METABOLOMES OF EMBRYO_DERIVED TERATOMAS TREATED WITH VALPROATE IN VIVO // Bookof Abstracts / Katalinić, Maja ; Dulić, Morana ; Stuparević , Igor (ur.).
Zagreb: Croatian Society of Biochemistry and Molecular Biology, 2019. str. 73-73 (poster, međunarodna recenzija, sažetak, znanstveni)


CROSBI ID: 1058208 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
BIOMARKERS DETECTED BY THE INFRARED SPECTROSCOPY IN SPENT MEDIA METABOLOMES OF EMBRYO_DERIVED TERATOMAS TREATED WITH VALPROATE IN VIVO

Autori
Plazibat, Milvija ; Katušić-Bojana, AnaHimerleich Perić, Marta ; Gamulin, Ozren ; Mario Rašić, Vedran Radonić, DĂƌŬŽŠkrabić, Maria Krajačić, Jure Krasić, Nino Sinčić, Gordana JurićͲLekić, Maja Balarin†, Floriana BulićͲ Jakuš Gamulin, Ozren ; Rašić, Mario ; Radonić, Vedran ; , Krajačić, Maria ; Krasić, Jure ; Sinči, Nino ; Jurić- Lekić, Gordana ; Balarin, Maja ; Bulić-Jakuš, Floriana

Kolaboracija
Croatian Society of Biochemistry and Molecular Biology

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Bookof Abstracts / Katalinić, Maja ; Dulić, Morana ; Stuparević , Igor - Zagreb : Croatian Society of Biochemistry and Molecular Biology, 2019, 73-73

ISBN
978-953-95551-7-5

Skup
Congress of the Croatian Society of Biochemistry and Molecular Biology, HDBMB2019 “Crossroads in Life Sciences”

Mjesto i datum
Lovran, Hrvatska, 25-28.09.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
embryo , teratomas, spectrosccopy

Sažetak
Spectroscopy screening of metabolomes detect biological activity of the epigenetic-valproate - derived teratomas in vivo.Principal component analysis of FTIR results showed that spent media metabolomes formed well‐separated clusters reflecting the treatment and day of cultivation. In metabolomes of VPA‐treated teratomas, we found elevation of previously described histone acetylation biomarkers [amide I α‐helix and A(CH3)/A(CH2)]) with apoptotic biomarkers within the amide I region for β‐sheets, and unordered and CH2 vibrations of lipids. VPA may be proposed for therapy of the undifferentiated component of teratoma tumors and this biological system completed by metabolome analysis, for a faster dual screening of antitumor/embryotoxic agents.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
108-1080399-0335 - Eksperimentalni embrionalni tumori i razvoj zametaka sisavaca in vitro i in vivo (Jakuš, Florijana, MZOS ) ( POIROT)

Ustanove:
Medicinski fakultet, Zagreb,
Opća bolnica Zabok,
Fakultet za dentalnu medicinu i zdravstvo, Osijek


Citiraj ovu publikaciju

(Croatian Society of Biochemistry and Molecular Biology) Plazibat, Milvija; Katušić-Bojana, AnaHimerleich Perić, Marta; Gamulin, Ozren; Mario Rašić, Vedran Radonić, DĂƌŬŽŠkrabić, Maria Krajačić, Jure Krasić, Nino Sinčić, Gordana JurićͲLekić, Maja Balarin†, Floriana BulićͲ Jakuš Gamulin, Ozren; Rašić, Mario; Radonić, Vedran; , Krajačić, Maria; Krasić, Jure; Sinči, Nino; Jurić- Lekić, Gordana et al.
BIOMARKERS DETECTED BY THE INFRARED SPECTROSCOPY IN SPENT MEDIA METABOLOMES OF EMBRYO_DERIVED TERATOMAS TREATED WITH VALPROATE IN VIVO // Bookof Abstracts / Katalinić, Maja ; Dulić, Morana ; Stuparević , Igor (ur.).
Zagreb: Croatian Society of Biochemistry and Molecular Biology, 2019. str. 73-73 (poster, međunarodna recenzija, sažetak, znanstveni)
(Croatian Society of Biochemistry and Molecular Biology) (Croatian Society of Biochemistry and Molecular Biology) Plazibat, M., Katušić-Bojana, AnaHimerleich Perić, Marta, Gamulin, O., Mario Rašić, Vedran Radonić, DĂƌŬŽŠkrabić, Maria Krajačić, Jure Krasić, Nino Sinčić, Gordana JurićͲLekić, Maja Balarin†, Floriana BulićͲ Jakuš Gamulin, Ozren, Rašić, M., Radonić, V., , Krajačić, Maria, Krasić, J., Sinči, N. & Jurić- Lekić, G. (2019) BIOMARKERS DETECTED BY THE INFRARED SPECTROSCOPY IN SPENT MEDIA METABOLOMES OF EMBRYO_DERIVED TERATOMAS TREATED WITH VALPROATE IN VIVO. U: Katalinić, M., Dulić, M. & Stuparević , I. (ur.)Bookof Abstracts.
@article{article, year = {2019}, pages = {73-73}, keywords = {embryo , teratomas, spectrosccopy}, isbn = {978-953-95551-7-5}, title = {BIOMARKERS DETECTED BY THE INFRARED SPECTROSCOPY IN SPENT MEDIA METABOLOMES OF EMBRYO\_DERIVED TERATOMAS TREATED WITH VALPROATE IN VIVO}, keyword = {embryo , teratomas, spectrosccopy}, publisher = {Croatian Society of Biochemistry and Molecular Biology}, publisherplace = {Lovran, Hrvatska} }
@article{article, year = {2019}, pages = {73-73}, keywords = {embryo , teratomas, spectrosccopy}, isbn = {978-953-95551-7-5}, title = {BIOMARKERS DETECTED BY THE INFRARED SPECTROSCOPY IN SPENT MEDIA METABOLOMES OF EMBRYO\_DERIVED TERATOMAS TREATED WITH VALPROATE IN VIVO}, keyword = {embryo , teratomas, spectrosccopy}, publisher = {Croatian Society of Biochemistry and Molecular Biology}, publisherplace = {Lovran, Hrvatska} }




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