engleski

PRIMARY DYSMENORRHEA AND VITAMIN D INSUFFICIENCY IN YOUNG WOMEN

PRIMARY DYSMENORRHEA AND VITAMIN D INSUFFICIENCY IN YOUNG WOMEN Co-authors B. Miskic1, V. Cosic2, I. Rajkovaca1, K. Cvitkusic-Lukenda3, M. Knezevic-Pravecek3. 1Faculty of Dental Medicine and Health- Osijek, of gastroneterologie- endocrinologie and diabetiologie-GH dr Josip Bencevic Sl.Brod, Slav. Brod, Croatia. 2Faculty of Dental Medicine and Health- Osijek, Polyclinic Cosic- Slav. Brod- Croatia, Slav. Brod, Croatia. 3Faculty of Dental Medicine and Health- Osijek, of cardiology-GH dr Josip Bencevic Sl.Brod, Slav. Brod, Croatia. Abstract text Background and Aims: Vitamin D deficiency is often found in many autoimunological disease like diabetes, tiroiditis so as in other different state like depression, breast tenderness, general fatigue. Recent studies shown connection of vitamin D insufficiency with primary dysmenorrhea in young women. Aims: We wanted to estimate difference in serum 25-hydroxyvitamin D3 levels between young women with primary dysmenorrhea and healthy controls. Methods:We have analyzed 64 patients with primary dysmenorhhea and 64 healthy controls comparable in age, height, weight, body mass index (BMI). We measured vitamin D levels, serum calcium, paratyroid hormon. All of them completed a questionnaire about menstruation. The severity of dysmenorrhea pain was assessed by using visual analogue scale (VAS) scoring system which is based on numerical rating between 1 and 10. Results: 62% dysmenorrhoic women and 20%healthy controls had vitamin D insufficiency, (19, 21 ±.1, 4)nmol/L, 27% dysmenorrhoic and 50% healthy controls had defficiency ( 45, 23± 3, 28)nmol/L. Women with vitamin D insufficiency had statisticaly significantly intensity of menstrual bleeding and duration of cycle higer (p-= 0, 004, p<0.05) and longer ( p=0, 001, p<0.05), than normal controls. VAS score was also statisticaly significant between dysmenorrhoic women and controls ( 7, 4±1, 6 and 2, 1± 1, 1), p 0, 001 , p<0.05, We had had a negative correlation between vitamin D levels and VAS score. Conclusions: . The significant correlation between vitamin D levels and VAS scores either as low serum level of vitamin D of the dysmenorrhea women shows the possible role of vitamin D deficiency in primary dysmenorrhea at young women

dysmenorrhea. vit D insufficiency, young women

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