Pharmacogenomics at the center of precision medicine: challenges and perspective in an era of Big Data (CROSBI ID 277265)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Primorac, Dragan ; Bach-Rojecky, Lidija ; Vađunec, Dalia ; Juginović, Alen ; Žunić, Katarina ; Matišić, Vid ; Skelin, Andrea ; Arsov, Borna ; Boban, Luka ; Erceg, Damir ; Ivkošić, Ivana Erceg ; Molnar, Vilim ; Ćatić, Jasmina ; Mikula, Ivan ; Boban, Ljubica ; Primorac, Lara ; Esquivel, Bernard ; Donaldson, Morgan
engleski
Pharmacogenomics at the center of precision medicine: challenges and perspective in an era of Big Data
About Abstract Pharmacogenomics (PGx) is one of the core elements of personalized medicine. PGx information reduces the likelihood of adverse drug reactions and optimizes therapeutic efficacy. St Catherine Specialty Hospital in Zagreb/Zabok, Croatia has implemented a personalized patient approach using the RightMed® Comprehensive PGx panel of 25 pharmacogenes plus Facor V Leiden, Factor II and MTHFR genes, which is interpreted by a special counseling team to offer the best quality of care. With the advent of significant technological advances comes another challenge: how can we harness the data to inform clinically actionable measures and how can we use it to develop better predictive risk models? We propose to apply the principles artificial intelligence to develop a medication optimization platform to prevent, manage and treat different diseases.
artificial intelligence ; personilized medicine ; pharmacogenomics ; therapy optimization
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Podaci o izdanju
Povezanost rada
Temeljne medicinske znanosti