engleski

Opsoclonus-myoclonus Syndrome – a case report.

Opsoclonus myoclonus syndrome is defined by opsoclonus, myoclonus, and ataxia, behavioral and sleep problems. Mostly, it is paraneoplastic associated with different kind of cancers, in children mostly with neuroblastic tumors. Case Report: We report the case of a 2 -year-old girl who developed an ataxia without a known trigger.Hospital submission was necessary by persistent ataxia and suspected encephalitis. Different diagnostic tools (CCT, cMRI, lumbal puncture, search for auto antibodies, and virological diagnostic) showed normal results. The next days, the girl besides the ataxia showed muscular hypotonia, tremor, sleep and behavioral problems, and some strange ocular movements but not real opsoclonus. A neuroblastic tumor could not be found. Under therapy with dexamethasone (pulse, 20 mg/m2) which resulted in a good neurologic improvement. During the first three cycles, there was always a short worsening with recurrence of the ataxia , sleep disturbance and behavioral problems directly before dexamethasone was given. Meanwhile there is a constant improvement. We show videos from the first signs of opsoclonus myoclonus sy directly after first corticosteroid treatment up to the current state after 3 months.

opsoclonus-myoclonus syndrome

nije evidentirano