engleski

Haemodynamic effects and the visibility of the surgical field after lidocaine infiltration during septoplasty under general anaesthesia

Background and Purpose: The aim of this study was to determine the effect of local infiltration of adrenaline- containing lidocaine solution during septoplasty under general anaesthesia on systemic haemodynamics and the visibility of the operative field, and to compare it to the topical application of ephedrine. Patients and Methods: A retrospective, comparative, non-randomised, open study on 72 ASA physical status I and II patients, aged 20 to 73 years, scheduled for septoplasty was performed. Lidocaine/adrenaline-ephedrine group (group LA- E ; n=18) received four cotton pledgets soaked with 1 % ephedrine, andthenthesubmucosalinfiltrationof2%l idocainecontaining adrenaline solution (2ml) plus plain 2% lidocaine solution (5ml). Lidocaine/adrenaline group (LA group ; n=25) received the submucosal infiltrationof2%lidocainecontainingadrenalineso lution(2ml)plusplain2% lidocaine solution (5ml). Ephedrine group (E group ; n=29) received four cottonpledgetssoakedwith1%ephedrine.Heartrate(H R)andmeanarterial pressure (MAP) were recorded at predetermined time intervals. Bleeding in the surgical field was rated according to a 6- point scale. Results: LA and LA-E groups showed significant lower HR and MAP comparedtoE- group.LAgroupshowedonlyslightoscillationsinHR.A verage bleeding score was 2.28±0.83 in LA-E, 2.08±0.81 in LA and 3.14±0.74 in E group (p<0.001). Conclusions:Wedemonstratedthatinfiltrationoflid ocainewithadrenaline has statistically and clinically better impact on systemic haemodynamics and visibility of the surgical field than that achieved by topical application of ephedrine alone.

Anaesthesia, general ; anaesthesia ; local ; adrenaline ; nasal septum ; surgical procedures ; ephedrne

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