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Extremely low birth weight infant, late morbidities and health outcomes (CROSBI ID 276200)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Papazovska Cherepnalkovski, Anet ; Bucat, Marija ; Furlan, Ivanka ; Pavlov, Vesna ; Družić, Mila ; Budimir, Majda ; Brajkovic, Luka Extremely low birth weight infant, late morbidities and health outcomes // Paediatria Croatica, 62 (Supl 1) (2018), 22-27

Podaci o odgovornosti

Papazovska Cherepnalkovski, Anet ; Bucat, Marija ; Furlan, Ivanka ; Pavlov, Vesna ; Družić, Mila ; Budimir, Majda ; Brajkovic, Luka

engleski

Extremely low birth weight infant, late morbidities and health outcomes

Extremely low birth weight infants (ELBW) are those of birth weight of less than 1000 g and are usually born at ≤27 weeks’ gestation. We identified several major contributors to late morbidity in this group, namely bronchopulmonary dysplasia (BPD), late- onset infections, necrotizing enterocolitis, central nervous system manifestations, retinopathy (ROP) and anemia of prematurity. We estimated incidence and severity for each of these manifestations among our 41 study subjects of ELBW. We found low incidence of BPD- 7%. Severe ROP requiring laser photocoagulation and/or bevcizumab treatment was observed in 17.1% patients. Intraventricular hemorrhage (any grade) was noted in 11 (29%) of the patients. Diffuse cystic periventricular leucomalacia was present in only 1 patient (2.4%) of the deceased group. We showed high incidence of late-onset infection (73%), most frequent pathogens were Meticilin Resistant Staphylococus Epidermidis and Acinetobacter baumanii. Candida was infrequently present in hemoculture due to the strict policy of prophylaxis with fluconazole. No cases of hydrocephalus or necrotizing enterocolitis were described. A larger study group is needed to draw conclusions on morbidities’ incidences and association with departments’ treatment strategies. We concluded that, specific follow up goals should be set for these ELBW infants upon discharge, most importantly for early identification of developmental disabilities and identification and treatment of medical complications. Close cooperation is required between neonatologists and the subspecialties further involved in follow up of these children.

extremely low birth weight infants ; late morbidities ; follow up ; University Hospital of Split

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Podaci o izdanju

62 (Supl 1)

2018.

22-27

objavljeno

1330-1403

1846-405X

Povezanost rada

Kliničke medicinske znanosti

Indeksiranost