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Pregled bibliografske jedinice broj: 1052294

Challenges in anesthesia personalization: resolving the pharmacogenomic puzzle


Bach-Rojecky, Lidija; Vađunec, Dalia; Lozić, Marin; Žunić, Katarina; Špoljar, Giorgina Gasparini; Čutura, Tomislav; Erceg, Damir; Primorac, Dragan
Challenges in anesthesia personalization: resolving the pharmacogenomic puzzle // Personalized Medicine, 16 (2019), 6; 511-525 doi:10.2217/pme-2019-0056 (međunarodna recenzija, članak, znanstveni)


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Naslov
Challenges in anesthesia personalization: resolving the pharmacogenomic puzzle

Autori
Bach-Rojecky, Lidija ; Vađunec, Dalia ; Lozić, Marin ; Žunić, Katarina ; Špoljar, Giorgina Gasparini ; Čutura, Tomislav ; Erceg, Damir ; Primorac, Dragan

Izvornik
Personalized Medicine (1741-0541) 16 (2019), 6; 511-525

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
anesthesia ; epigenetics ; genotype ; inhalational anesthetics ; intravenous anesthetics ; neuromuscular blockers ; opioids ; pharmacological characteristics ; sedatives

Sažetak
Clinicians are witnessing differences in the doses required for induction and maintenance of anesthesia, as well as prolonged recovery in some patients. Predictable factors like patient characteristics, factors related to the procedure, pharmacological characteristics of anesthetics and adjunctive drugs, might explain some of the observed differences. However, the role of various polymorphisms of genes encoding for drugs' molecular targets, transporters and metabolic enzymes can have a significant impact on anesthesia outcome, too. In the present paper, we critically discuss pharmacological characteristics of the most common drugs used in anesthesia, with a focus on the possible genetic background of unpredictable diversities in anesthesia outcomes.

Izvorni jezik
Engleski



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Rijeka,
Fakultet za dentalnu medicinu i zdravstvo, Osijek

Profili:

Avatar Url Lidija Bach-Rojecky (autor)

Avatar Url Dragan Primorac (autor)

Avatar Url Damir Erceg (autor)

doi

Citiraj ovu publikaciju

Bach-Rojecky, Lidija; Vađunec, Dalia; Lozić, Marin; Žunić, Katarina; Špoljar, Giorgina Gasparini; Čutura, Tomislav; Erceg, Damir; Primorac, Dragan
Challenges in anesthesia personalization: resolving the pharmacogenomic puzzle // Personalized Medicine, 16 (2019), 6; 511-525 doi:10.2217/pme-2019-0056 (međunarodna recenzija, članak, znanstveni)
Bach-Rojecky, L., Vađunec, D., Lozić, M., Žunić, K., Špoljar, G., Čutura, T., Erceg, D. & Primorac, D. (2019) Challenges in anesthesia personalization: resolving the pharmacogenomic puzzle. Personalized Medicine, 16 (6), 511-525 doi:10.2217/pme-2019-0056.
@article{article, year = {2019}, pages = {511-525}, DOI = {10.2217/pme-2019-0056}, keywords = {anesthesia, epigenetics, genotype, inhalational anesthetics, intravenous anesthetics, neuromuscular blockers, opioids, pharmacological characteristics, sedatives}, journal = {Personalized Medicine}, doi = {10.2217/pme-2019-0056}, volume = {16}, number = {6}, issn = {1741-0541}, title = {Challenges in anesthesia personalization: resolving the pharmacogenomic puzzle}, keyword = {anesthesia, epigenetics, genotype, inhalational anesthetics, intravenous anesthetics, neuromuscular blockers, opioids, pharmacological characteristics, sedatives} }
@article{article, year = {2019}, pages = {511-525}, DOI = {10.2217/pme-2019-0056}, keywords = {anesthesia, epigenetics, genotype, inhalational anesthetics, intravenous anesthetics, neuromuscular blockers, opioids, pharmacological characteristics, sedatives}, journal = {Personalized Medicine}, doi = {10.2217/pme-2019-0056}, volume = {16}, number = {6}, issn = {1741-0541}, title = {Challenges in anesthesia personalization: resolving the pharmacogenomic puzzle}, keyword = {anesthesia, epigenetics, genotype, inhalational anesthetics, intravenous anesthetics, neuromuscular blockers, opioids, pharmacological characteristics, sedatives} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
  • Scopus


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