engleski

Wine and obesity: animal model

It is still controversial whether alcohol intake represents a risk factor for weight gain and obesity. Based on recent reviews, it seems that only heavy drinking is positively related with the weight gain. Also, it appears that the type of alcoholic beverage is an important element in modifying the effect of alcohol consumption on the weight gain with wine being regarded as an alcoholic beverage with more favorable effects. Among proposed explanations for this is possible role of wine phenolics on food intake, gastrointestinal energy harvest and/or nutrients metabolism. In order to evaluate this assumption, we compared effects of 4 weeks consumption of standard (W) and macerated white wine (MW) on weight gain in rats. One and three months old Sprague-Dawley male rats were used. Each age group was subdivided into: water-only-drinking controls (C), W and MW drinking animals. Daily wine and total liquid consumption, food intake and body weight were measured, and energy intake and feed efficiency index were calculated. Results showed that in both age categories wine- drinking animals gained less weight in comparison to C, regardless of wines’ polyphenols content. Wine consumption was associated with decreased food intake implying that additional calories provided by wine partially compensate for calories from other foodstuff. Although our results are indicative of the major role of non- phenolic constituents of the wines, probably ethanol, the present study cannot exclude the modifying role of wine phenolics on weight gain as the animals consuming MW had lower total energy intake in comparison to other groups.

White wine ; Macerated wine ; Weight gain

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