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Cas3 protein - a review of a multi-tasking machine (CROSBI ID 275397)

Prilog u časopisu | pregledni rad (znanstveni) | međunarodna recenzija

Liu, He ; James, Michael St. John ; Radovcic, Marin ; Ivancic-Bace, Ivana ; Bolt, Edward L. Cas3 protein - a review of a multi-tasking machine // Genes, 11 (2020), 208; 1-14. doi: 10.3390/genes11020208

Podaci o odgovornosti

Liu, He ; James, Michael St. John ; Radovcic, Marin ; Ivancic-Bace, Ivana ; Bolt, Edward L.

engleski

Cas3 protein - a review of a multi-tasking machine

Cas3 has essential functions in CRISPR immunity but its other activities and roles, in vitro and in cells, are less widely known. We offer a concise review of the latest understanding and the questions arising from studies of Cas3 mechanism during CRISPR immunity, and highlight recent attempts at using Cas3 for genetic editing. We then spotlight involvement of Cas3 in other aspects of cell biology, for which understanding is lacking - these focus on CRISPR systems as regulators of cellular processes in addition to defense against mobile genetic elements.

CRISPR ; Cas3 ; helicase ; nuclease ; biofilm

HRZZ projekt

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Podaci o izdanju

11 (208)

2020.

1-14

objavljeno

2073-4425

10.3390/genes11020208

Povezanost rada

Biologija

Poveznice
Indeksiranost