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Development of a prediction model for postoperative pneumonia A multicentre prospective observational study (CROSBI ID 275199)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

(PERISCOPE group of the European Society of Anaesthesiology (ESA) Clinical Trial Network) Russotto, Vincenzo ; Sabate, Sergi ; Canet, Jaume ; Langeron, Olivier ; de Abreu, Marcelo Gama ; Gallart, Lluis ; Javier Belda, F. ; Pelosi, Paolo ; Hoeft, Andreas ; Mazo, Valentin et al. Development of a prediction model for postoperative pneumonia A multicentre prospective observational study // European journal of anaesthesiology, 36 (2019), 2; 93-104. doi: 10.1097/EJA.0000000000000921

Podaci o odgovornosti

Russotto, Vincenzo ; Sabate, Sergi ; Canet, Jaume ; Langeron, Olivier ; de Abreu, Marcelo Gama ; Gallart, Lluis ; Javier Belda, F. ; Pelosi, Paolo ; Hoeft, Andreas ; Mazo, Valentin ; Leva, Brigitte ; Burimi, Jonela ; Halefi, Toma ; Hoxha, Aleksander ; Pilika, Kliti ; Selmani, Imelda ; Daout, Ve'ronique ; Gauthier, Caroline ; Kahn, David ; Momeni, Mona ; Watremez, Christine ; Straus, Slavenka ; Djonovic-manovic, Dejana ; Juros-Zovko, Marina ; Komen-Usljebrka, Helga ; Orlic, Vlasta ; Stuck, Ivana ; Balakova, Lenka ; Kosinova, Martina ; Krikava, Ivo ; Stoudek, Roman ; Stourac, Petr ; Zadrazilova, Katarina ; Janvekar, Sanober ; Karjagin, Juri ; Roivassepp, Kadri ; Sormus, Alar ; Cuvillon, Philippe ; Ibanez-Esteve, Cristina ; Raux, Mathieu ; Nicolas-Robin, Armelle ; Winter, Andre ; Brunier, Malte ; Engelhard, Kristin ; Feldmann, Rita Laufenberg ; Lindemann, Raphaele ; Mauff, Susanne ; Sebastiani, Anne ; Zamperoni, Camila ; Hoeft, Andreas ; Kessler, Florian ; Wittmann, Maria ; Bluth, Thomas ; Guldner, Andreas ; Kiss, Thomas ; Braz, Kristina ; Ruszkai, Csilla ; Micaglio, Massimo ; Ori, Carlo ; Parotto, Matteo ; Persona, Paolo ; Giuseppe, Coletta ; Carnesecchi, Paolo ; Lazzeroni, Denise ; Lorenzi, Irene ; Castellani, Gianluca ; Sances, Daniele ; Spano, Gianluca ; Tredici, Stefano ; Vezzoli, Dario ; Brunetti, Iole ; Di Noto, Anna ; Gratarola, Angelo ; Molin, Alexandre ; Montagnani, Luca ; Pellerano, Giulia ; Pelosi, Paolo ; Fusari, Maurizio ; Camici, Laura ; Guzzetti, Luca ; Marangoni, Fabio ; Severgnini, Paolo ; Di Mauro, Piero ; Rapido, Francesca ; Tommasino, Concezione ; Nemme, Ieva ; Nemme, Janis ; Blieka, Justinas ; Borodiciene, Jurgita ; Budryte, Brigita ; Karbonskiene, Aurika ; Kiudulaite, Inga ; Milieskaite, Egle ; Rasimaviciute, Renata ; Sireviciene, Ugne ; Stasaityte, Ramune ; Usas, Edgaras ; Zarskiene, Giedre ; Kontrimaviciute, Egle ; Sipylaite, Jurate ; Tomkute, Gabija ; Bardea, Petra ; Klop, Marco ; Koch, Marc ; Bozilow, Dominika ; Goch, Robert ; Bonifacio, Joao ; Marques, Sofia ; dos Santos Ralha, Tania Teresa ; Alves, Daniel ; Carvalho, Ines ; Da Cruz Parente, Josefina Suzana ; Tome, Sara ; Carmona, Cristina ; Costa, Miranda ; Lina, Maria ; Sierra, Sofia ; Balcan, Alina ; Cindea, Iulia ; Gherghina, Viorel Ionel ; Grasa, Catalin ; Copotoiu, Ruxandra ; Copotoiu, Sanda-Maria ; Kovacs, Judit ; Szederjesi, Janos ; Theil, Arthur ; Filipescu, Daniela ; Grytsan, Alexey ; Kapkan, Tatiana ; Rostovtsev, Sergey ; Yushkova, Anastasia ; Calderon, Ricardo ; Cacho, Elena ; Marginet, Carolina ; Monedero, Pablo ; Jose Yepes, Maria ; Esparza Minana, Jose Miguel ; Granell Gil, Manuel ; Rico Portoles, Gabriel ; Lisi, Alberto ; Perez, Gisela ; Poch, Nuria ; Arganaraz Quinteros, Mauricio Roberto ; Font Bosch, Carme ; Torrellardona Llobera, Jordi ; Sierra, Pilar ; Matute, Mercedes ; Alcon Dominguez, Amalia ; Jose Arguis, Maria ; Belda, Isabel ; Carrero, Enrique ; Moreno, Jacobo ; Rovira, Irene ; Ubre, Marta ; Castillo, Roberto ; Herrero, Silvia ; Ballester Lujan, Maria Teresa ; Carbonell, Jose ; Gencheva, Geri ; Gutierrez, Andrea ; Llorens, Julio ; Machado, Sofia ; Llobell, Francisca ; Paz Martin, Daniel ; Javier Garcia-Miguel, Francisco ; Perez Garcia, Anibal ; Company, Roque ; Ahamdanech Idrissi, Aixa ; del Fresno Canaveras, Josefina ; Navarro Martinez, Jose Alejandro ; Paya Martinez, Estefania ; Sanchez Garcia, Ester ; Vera Bella, Jorge ; India Aldana, Inmaculada ; Manuel Campos, J. ; Pelaez Vaamonde, Xavier ; Torra, Montserrat ; Arroyo, Raquel ; Carlos Cabrera, Juan ; Carazo Cordobes, Jesus ; Gallart, Lluis ; Rojo, Amelia ; Javier Santiveri, Francisco ; Gonzalez, Miriam ; Jimenez, Anabel ; Jimenez, Yolanda ; Marti, Agnes ; Moret, Enrique ; Rodriguez Nunez, Monica ; Velasco, Joaquin ; Calderon, Adriana ; Gonzalez, Matide ; Gonzalez, Olga ; Hermira Anchuelo, Ana ; Lopez, Eloisa ; Sanchez, Esther ; Aznarez Zango, Blanca ; Garcia Corral, Francisco Jose ; Mata Mena, Esperanza ; Planas Roca, Antonio ; Ayala Soto, Raquel Fernandez Rocio ; Quintana, Borja ; Rabanal Llevot, Jose Manuel ; Williams Camus, Monica Mercedes ; Palacios Blanco, Alba ; Largo Ruiz, Angela ; Rico Feijoo, Jesus ; Castellano Garijo, Elvira ; Belmonte Cuenca, Julio ; Bonet Binimelis, Marcos Jose ; Grigorov, Ivaylo ; Lluis Aguilar, Josep ; De Nadal Clanchet, Miriam ; Guerrero Vinas, Encarnacion ; Manrique Muniz, Susana ; Martin Mora, Victor ; Munar Bauza, Francisca ; Nunez Aguado, Sonia ; Olive Vidal, Montserrat ; Panos Gozalo, Maria Luisa ; Sanchez Marin, Marcos ; Suescun Lopez, Maria Carmen ; Maino, Paolo ; Yevstratov, Yevhen Eugene ; Kucukgoncu, Semra ; Senturk, Nuzhet Mert ; Ulke, Zerrin Sungur

PERISCOPE group of the European Society of Anaesthesiology (ESA) Clinical Trial Network

engleski

Development of a prediction model for postoperative pneumonia A multicentre prospective observational study

BACKGROUND Postoperative pneumonia is associated with increased morbidity, mortality and costs. Prediction models of pneumonia that are currently available are based on retrospectively collected data and administrative coding systems. OBJECTIVE To identify independent variables associated with the occurrence of postoperative pneumonia. DESIGN A prospective observational study of a multicentre cohort (Prospective Evaluation of a RIsk Score for postoperative pulmonary COmPlications in Europe database). SETTING Sixty-three hospitals in Europe. PATIENTS Patients undergoing surgery under general and/or regional anaesthesia during a 7-day recruitment period. MAIN OUTCOME MEASURE The primary outcome was postoperative pneumonia. Definition: the need for treatment with antibiotics for a respiratory infection and at least one of the following criteria: new or changed sputum ; new or changed lung opacities on a clinically indicated chest radiograph ; temperature more than 38.3 degrees C ; leucocyte count more than 12 000 mu l(-1). RESULTS Postoperative pneumonia occurred in 120 out of 5094 patients (2.4%). Eighty-two of the 120 (68.3%) patients with pneumonia required ICU admission, compared with 399 of the 4974 (8.0%) without pneumonia (P < 0.001). We identified five variables independently associated with postoperative pneumonia: functional status [odds ratio (OR) 2.28, 95% confidence interval (CI) 1.58 to 3.12], pre-operative SpO(2) values while breathing room air (OR 0.83, 95% CI 0.78 to 0.84), intra-operative colloid administration (OR 2.97, 95% CI 1.94 to 3.99), intra-operative blood transfusion (OR 2.19, 95% CI 1.41 to 4.71) and surgical site (open upper abdominal surgery OR 3.98, 95% CI 2.19 to 7.59). The model had good discrimination (c- statistic 0.89) and calibration (Hosmer- Lemeshow P = 0.572). CONCLUSION We identified five variables independently associated with postoperative pneumonia. The model performed well and after external validation may be used for risk stratification and management of patients at risk of postoperative pneumonia.

PULMONARY COMPLICATIONS ; HYDROXYETHYL STARCH ; HEMORRHAGIC-SHOCK ; RISK ; RESUSCITATION ; VALIDATION ; INFECTION ; SCORE

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Podaci o izdanju

36 (2)

2019.

93-104

objavljeno

0265-0215

1365-2346

10.1097/EJA.0000000000000921

Povezanost rada

nije evidentirano

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