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Pregled bibliografske jedinice broj: 1048147

Diagnostic Delays in Children With Coeliac Disease in the Central European Region


Riznik, Petra; De Leo, Luigina; Dolinsek, Jasmina; Gyimesi, Judit; Klemenak, Martina; Koletzko, Berthold; Koletzko, Sibylle; Korponay-Szabó, Ilma Rita; Krencnik, Tomaz; Not, Tarcisio et al.
Diagnostic Delays in Children With Coeliac Disease in the Central European Region // Journal of pediatric gastroenterology and nutrition, 69 (2019), 4; 443-448 doi:10.1097/mpg.0000000000002424 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1048147 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Diagnostic Delays in Children With Coeliac Disease in the Central European Region

Autori
Riznik, Petra ; De Leo, Luigina ; Dolinsek, Jasmina ; Gyimesi, Judit ; Klemenak, Martina ; Koletzko, Berthold ; Koletzko, Sibylle ; Korponay-Szabó, Ilma Rita ; Krencnik, Tomaz ; Not, Tarcisio ; Palcevski, Goran ; Sblattero, Daniele ; Vogrincic, Matej ; Werkstetter, Katharina Julia ; Dolinsek, Jernej

Izvornik
Journal of pediatric gastroenterology and nutrition (0277-2116) 69 (2019), 4; 443-448

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Central Europe ; children ; coeliac disease ; diagnostic delays

Sažetak
Objectives: Coeliac disease (CD) is a systemic autoimmune disorder affecting about 1% of the population. Many patients remain undiagnosed or are diagnosed with substantial delay. We assessed diagnostic delays in symptomatic CD children in Central Europe (CE). Methods: Paediatric gastroenterologists in 5 CE countries retrospectively reported data of their patients diagnosed in 2016. Age at first CD-related symptom(s), first visit to paediatric gastroenterologist and confirmed diagnosis were used to determine diagnostic delays. Results: Data from 393 children (65% girls, median age 7 years, range 7 months to 18.5 years) from Croatia, Hungary, Germany, Italy, and Slovenia were analysed. Median duration from first symptom(s) to visit to paediatric gastroenterologist was 5 months (range 0–10 years ; preschool 4 months, school-aged 5 months), and further duration until final diagnosis was 1 month (range 0–5 years) with significant regional differences (P < 0.001). Median diagnostic delay was 6 months (range 0–10 years ; preschool 5 months, school-aged 7 months). Type of clinical presentation had little, however, significant effect on delays. Reduced body mass in delays longer than 3 years compared with delays shorter than 1 year was found (z score −0.93 vs −0.39, P < 0.05). Conclusions: Time from first symptoms to CD diagnosis in children in 5 CE countries is slightly shorter compared with few other small paediatric studies, and significantly shorter than reported for adults. Nevertheless, delays of more than 3 years in 6.6% of children are worrisome. Raising awareness about the variable symptoms and implementation of reliable diagnostic tools will further reduce diagnostic delays

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Rijeka,
Klinički bolnički centar Rijeka,
Fakultet zdravstvenih studija u Rijeci

Profili:

Avatar Url Goran Palčevski (autor)

Citiraj ovu publikaciju

Riznik, Petra; De Leo, Luigina; Dolinsek, Jasmina; Gyimesi, Judit; Klemenak, Martina; Koletzko, Berthold; Koletzko, Sibylle; Korponay-Szabó, Ilma Rita; Krencnik, Tomaz; Not, Tarcisio et al.
Diagnostic Delays in Children With Coeliac Disease in the Central European Region // Journal of pediatric gastroenterology and nutrition, 69 (2019), 4; 443-448 doi:10.1097/mpg.0000000000002424 (međunarodna recenzija, članak, znanstveni)
Riznik, P., De Leo, L., Dolinsek, J., Gyimesi, J., Klemenak, M., Koletzko, B., Koletzko, S., Korponay-Szabó, I., Krencnik, T. & Not, T. (2019) Diagnostic Delays in Children With Coeliac Disease in the Central European Region. Journal of pediatric gastroenterology and nutrition, 69 (4), 443-448 doi:10.1097/mpg.0000000000002424.
@article{article, year = {2019}, pages = {443-448}, DOI = {10.1097/mpg.0000000000002424}, keywords = {Central Europe, children, coeliac disease, diagnostic delays}, journal = {Journal of pediatric gastroenterology and nutrition}, doi = {10.1097/mpg.0000000000002424}, volume = {69}, number = {4}, issn = {0277-2116}, title = {Diagnostic Delays in Children With Coeliac Disease in the Central European Region}, keyword = {Central Europe, children, coeliac disease, diagnostic delays} }
@article{article, year = {2019}, pages = {443-448}, DOI = {10.1097/mpg.0000000000002424}, keywords = {Central Europe, children, coeliac disease, diagnostic delays}, journal = {Journal of pediatric gastroenterology and nutrition}, doi = {10.1097/mpg.0000000000002424}, volume = {69}, number = {4}, issn = {0277-2116}, title = {Diagnostic Delays in Children With Coeliac Disease in the Central European Region}, keyword = {Central Europe, children, coeliac disease, diagnostic delays} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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