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Pregled bibliografske jedinice broj: 1048053

Is There a Role of Using a Rapid Finger Prick Antibody Test in Screening for Celiac Disease in Children?


Baraba Dekanić, Kristina; Butorac Ahel, Ivona; Ružman, Lucija; Dolinšek, Jasmina; Dolinšek, Jernej; Palčevski, Goran
Is There a Role of Using a Rapid Finger Prick Antibody Test in Screening for Celiac Disease in Children? // Gastroenterology Research and Practice, 2019 (2019), 1-5 doi:10.1155/2019/4504679 (međunarodna recenzija, članak, znanstveni)


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Naslov
Is There a Role of Using a Rapid Finger Prick Antibody Test in Screening for Celiac Disease in Children?

Autori
Baraba Dekanić, Kristina ; Butorac Ahel, Ivona ; Ružman, Lucija ; Dolinšek, Jasmina ; Dolinšek, Jernej ; Palčevski, Goran

Izvornik
Gastroenterology Research and Practice (1687-6121) 2019 (2019); 1-5

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
celiac disease ; glutens ; autoimmune diseases ; prevalence

Sažetak
Introduction. Celiac disease (CD) is an autoimmune disease triggered by gluten in genetically predisposed individuals. Despite the increasing prevalence of CD, many patients remain undiagnosed. Standard serology tests are expensive and invasive, so several point-of- care tests (POC) for CD have been developed. We aimed to determine the prevalence of CD in first-grade pupils in Primorje-Gorski Kotar County, Croatia, using a POC test. Methods. A Biocard celiac test that detects IgA antibodies to tissue transglutaminase in whole blood was used to screen for celiac disease in healthy first-grade children born in 2011 and 2012 who consumed gluten without restrictions. Results. 1478 children were tested, and none of them were tested positive with a rapid test. In 10 children (0, 6%), IgA deficiency has been suspected ; only 4 of them agreed to be tested further for total IgA, anti-tTG, and anti-DGP antibodies. IgA deficiency was confirmed in 3 patients, and in all 4 children, CD has been excluded. Conclusion. Our results have not confirmed the usefulness of the POC test in screening the general population of first-grade schoolchildren. Further research is needed to establish the true epidemiology of CD in Primorje-Gorski Kotar County and to confirm the value of the rapid test in comparison with standard antibody CD testin

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Rijeka,
Klinički bolnički centar Rijeka,
Fakultet zdravstvenih studija u Rijeci

Citiraj ovu publikaciju

Baraba Dekanić, Kristina; Butorac Ahel, Ivona; Ružman, Lucija; Dolinšek, Jasmina; Dolinšek, Jernej; Palčevski, Goran
Is There a Role of Using a Rapid Finger Prick Antibody Test in Screening for Celiac Disease in Children? // Gastroenterology Research and Practice, 2019 (2019), 1-5 doi:10.1155/2019/4504679 (međunarodna recenzija, članak, znanstveni)
Baraba Dekanić, K., Butorac Ahel, I., Ružman, L., Dolinšek, J., Dolinšek, J. & Palčevski, G. (2019) Is There a Role of Using a Rapid Finger Prick Antibody Test in Screening for Celiac Disease in Children?. Gastroenterology Research and Practice, 2019, 1-5 doi:10.1155/2019/4504679.
@article{article, year = {2019}, pages = {1-5}, DOI = {10.1155/2019/4504679}, keywords = {celiac disease, glutens, autoimmune diseases, prevalence}, journal = {Gastroenterology Research and Practice}, doi = {10.1155/2019/4504679}, volume = {2019}, issn = {1687-6121}, title = {Is There a Role of Using a Rapid Finger Prick Antibody Test in Screening for Celiac Disease in Children?}, keyword = {celiac disease, glutens, autoimmune diseases, prevalence} }
@article{article, year = {2019}, pages = {1-5}, DOI = {10.1155/2019/4504679}, keywords = {celiac disease, glutens, autoimmune diseases, prevalence}, journal = {Gastroenterology Research and Practice}, doi = {10.1155/2019/4504679}, volume = {2019}, issn = {1687-6121}, title = {Is There a Role of Using a Rapid Finger Prick Antibody Test in Screening for Celiac Disease in Children?}, keyword = {celiac disease, glutens, autoimmune diseases, prevalence} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
  • Scopus


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