Cataract as Early Ocular Complication in Children and Adolescents with Type 1 Diabetes Mellitus (CROSBI ID 274458)
Prilog u časopisu | pregledni rad (znanstveni) | međunarodna recenzija
Podaci o odgovornosti
Šimunović, Marko ; Paradžik, Martina ; Škrabić, Roko ; Unić, Ivana ; Bućan, Kajo ; Škrabić, Veselin
engleski
Cataract as Early Ocular Complication in Children and Adolescents with Type 1 Diabetes Mellitus
Cataract is a rare manifestation of ocular complication at an early phase of T1DM in the pediatric population. The pathophysiological mechanism of early diabetic cataract has not been fully understood ; however, there are many theories about the possible etiology including osmotic damage, polyol pathway, and oxidative stress. The prevalence of early diabetic cataract in the population varies between 0.7 and 3.4% of children and adolescents with T1DM. The occurrence of diabetic cataract in most pediatric patients is the first sign of T1DM or occurs within 6 months of diagnosis of T1DM. Today, there are many experimental therapies for the treatment of diabetic cataract, but cataract surgery continues to be a gold standard in the treatment of diabetic cataract. Since the cataract is the leading cause of visual impairment in patients with T1DM, diabetic cataract requires an initial screening as well as continuous surveillance as a measure of prevention and this should be included in the guidelines of pediatric diabetes societies.
adolescents ; children ; type 1 diabetes mellitus ; cataract
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Podaci o izdanju
2018
2018.
6763586
6
objavljeno
1687-8337
1687-8345
10.1155/2018/6763586
Povezanost rada
Kliničke medicinske znanosti