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A comparative study of antibacterial and antifungal efficacy of soft contact lens disinfecting solutions

The aim o f this study was to compare antibacterial and antifungal efficacy o f five soft contact lens disinfecting solutions. The following solutions were tested : Oxysept Comfort (Advanced Medical Optics), Nitilens One Step (Avizor), Opti-Free Express (Alcon Laboratories), Complete Moisture Plus (Advanced Medical Optics) and Nitilens All-in-one (Avizor). Their efficacy to disin fect saline solution experimentally contaminated with American Type Culture Collection (ATCC): Staphylococcus aureus (ATCC 2592 ), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 2785 ), Candida albicans (ATCC 90028) and Staphylococcus epidermidis (isolated from our laboratory) was tested . All study solutions reduced concentrations of bacteria and fungi below 1000 CFU/mL (reduction by 3 log and 1 log, respectively) after 8-hour overnight disinfection. However, there were differences in their disinfecting efficacy. Generally, all contact lens care solutions showed good disinfecting activity against the bacteria and fungi tested . Yet, the differences recorded in their antimicrobial activity may become more evident among non-compliant patients, and therefore the results of the study might be valuable when selecting appropriate solutions for contact lens wearers.

Antimicrobial ; Contact lens ; Disinfection ; Multipurpose contact lens solution

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