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Repeated Percutaneous Treatment of Massive Hepatic Cystic Echinococcosis in a Child (CROSBI ID 273859)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Balen Topić, Mirjana ; Skuhala, Tomislava ; Desnica, Boško ; Višković, Klaudija ; Drinković, Martin Repeated Percutaneous Treatment of Massive Hepatic Cystic Echinococcosis in a Child // Pediatrics, 142 (2018), 6; e20181254, 0. doi: 10.1542/peds.2018-1254

Podaci o odgovornosti

Balen Topić, Mirjana ; Skuhala, Tomislava ; Desnica, Boško ; Višković, Klaudija ; Drinković, Martin

engleski

Repeated Percutaneous Treatment of Massive Hepatic Cystic Echinococcosis in a Child

Because of mostly asymptomatic cyst growth and often-neglected nonspecific low-grade symptoms, many cases of cystic echinococcosis (CE) caused by Echinococcus granulosus in the pediatric population are diagnosed at school age, in an advanced and even complicated stage. In 2003, after 5 months of intermittent dull upper-right abdominal pain and nausea, a 13-year-old boy was diagnosed with massive liver CE, with ∼20 round-shaped double-walled medium-sized infective cysts, which permeated the whole liver. Because of their wide distribution across the liver tissue and the risky superficial position of some cysts, liver transplantation emerged as the optimal therapeutic option. Despite being described as only an exceptionally used method for CE, we subjected our patient on 4 occasions to a radiofrequency energy thermoablation (RFT) procedure similar to the one used for malignant neoplasms. In total, 9 superficially situated cysts were initially treated with RFT by using a 14-gauge outer needle and a temperature of 70°C for 8 minutes per cyst, and the remaining cysts were treated with the puncture- aspiration-instillation-reaspiration procedure, along with albendazole (15 mg/kg per day) therapy, for a period of 20 months. After 2 years of follow- up, 4 residual small-sized semisolidified cysts were seen in the liver, and the patient showed no signs of relapse. Although not routinely used, RFT, along with puncture-aspiration-instillation-reaspiration and prolonged albendazole therapy, has shown good tolerability and long-term efficacy in the treatment of multiple infective CE, which could suggest the usefulness of the RFT method beyond salvage situations in pediatric patients.

hepatic cystic echinococcosis ; percutaneous treatment ; child

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Podaci o izdanju

142 (6)

2018.

e20181254

0

objavljeno

0031-4005

1098-4275

10.1542/peds.2018-1254

Povezanost rada

Kliničke medicinske znanosti

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