engleski

Ferrocene derivatives of nucleobases

Organometallic nucleobase derivatives (OrDeNs) correspond to a new generation of conjugates in which metallocenes are linked to the basic structural elements of heredity. Due to their electrophoric and bioactive properties, OrDeNs are of use in (bio)analytical and medicinal chemistry. The preparation of OrDeNs is based on the copulation reaction between the organometallic part with a heterocyclic base, by using different linkers. The choice of fragments usually follows the target of the ever-growing diversity of structural motifs.

ferrocene, nucleobase, derivatives

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