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Pregled bibliografske jedinice broj: 1037474

Antioxidative potential of ferulic acid phenoxyl radical


Amić, Ana; Marković, Zoran; Dimitrić Marković, Jasmina M.; Milenković, Dejan; Stepanić, Višnja
Antioxidative potential of ferulic acid phenoxyl radical // Phytochemistry, 170 (2020), 112218, 8 doi:10.1016/j.phytochem.2019.112218 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1037474 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Antioxidative potential of ferulic acid phenoxyl radical

Autori
Amić, Ana ; Marković, Zoran ; Dimitrić Marković, Jasmina M. ; Milenković, Dejan ; Stepanić, Višnja

Izvornik
Phytochemistry (0031-9422) 170 (2020); 112218, 8

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Ferulic acid ; Phenoxyl radical ; Free radical ; Antioxidative mechanism ; Hydrogen atom transfer ; Radical coupling ; Dimerization ; Density functional theory

Sažetak
The vast majority of previous studies dealing with antioxidant potency of (poly)phenols does not investigate the fate of phenoxyl radical obtained after single free radical scavenging. We investigated possible pathways of inactivation of ferulic acid phenoxyl radical (FAPR) using DFT method. Direct coupling with a set of 10 physiologically important free radicals, H-atom donation and dimerization were analyzed by estimation of Gibbs free energy changes related to these processes. The former two processes are thermodynamically feasible to inactivate more dangerous free radicals such as hydroxyl, alkoxyl and carbon-centered radicals. Among dimerization reactions, the least energy demanding is formation of C-5-C-5 dimer of ferulic acid (FA), which has higher antiradical potency than FA itself. Obtained results reveal that FAPR, a priori considered as stable and unreactive, may contribute to the overall antioxidant activity of FA. This is a beneficial behavior, which makes FA a particularly valuable protector against oxidative stress. Hence, the contribution of phenoxyl radicals to the antioxidant activity of (poly)phenolic compounds should be taken into account, what has been scarcely considered until now.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Ustanove:
Institut "Ruđer Bošković", Zagreb,
Sveučilište u Osijeku - Odjel za kemiju

Profili:

Avatar Url Višnja Stepanić (autor)

Avatar Url Ana Amić (autor)

Citiraj ovu publikaciju

Amić, Ana; Marković, Zoran; Dimitrić Marković, Jasmina M.; Milenković, Dejan; Stepanić, Višnja
Antioxidative potential of ferulic acid phenoxyl radical // Phytochemistry, 170 (2020), 112218, 8 doi:10.1016/j.phytochem.2019.112218 (međunarodna recenzija, članak, znanstveni)
Amić, A., Marković, Z., Dimitrić Marković, J., Milenković, D. & Stepanić, V. (2020) Antioxidative potential of ferulic acid phenoxyl radical. Phytochemistry, 170, 112218, 8 doi:10.1016/j.phytochem.2019.112218.
@article{article, year = {2020}, pages = {8}, DOI = {10.1016/j.phytochem.2019.112218}, chapter = {112218}, keywords = {Ferulic acid, Phenoxyl radical, Free radical, Antioxidative mechanism, Hydrogen atom transfer, Radical coupling, Dimerization, Density functional theory}, journal = {Phytochemistry}, doi = {10.1016/j.phytochem.2019.112218}, volume = {170}, issn = {0031-9422}, title = {Antioxidative potential of ferulic acid phenoxyl radical}, keyword = {Ferulic acid, Phenoxyl radical, Free radical, Antioxidative mechanism, Hydrogen atom transfer, Radical coupling, Dimerization, Density functional theory}, chapternumber = {112218} }
@article{article, year = {2020}, pages = {8}, DOI = {10.1016/j.phytochem.2019.112218}, chapter = {112218}, keywords = {Ferulic acid, Phenoxyl radical, Free radical, Antioxidative mechanism, Hydrogen atom transfer, Radical coupling, Dimerization, Density functional theory}, journal = {Phytochemistry}, doi = {10.1016/j.phytochem.2019.112218}, volume = {170}, issn = {0031-9422}, title = {Antioxidative potential of ferulic acid phenoxyl radical}, keyword = {Ferulic acid, Phenoxyl radical, Free radical, Antioxidative mechanism, Hydrogen atom transfer, Radical coupling, Dimerization, Density functional theory}, chapternumber = {112218} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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