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Pregled bibliografske jedinice broj: 1037436

Evaluation of cap-piercing technology for coagulation testing on Sysmex CS-2500 system


Komljenović, Sven; Zrinski Topić, Renata; Leniček Krleža, Jasna
Evaluation of cap-piercing technology for coagulation testing on Sysmex CS-2500 system // Clinical Chemistry and Laboratory Medicine
Berlin: De Gruyter, 2019. str. eA60-eA61 (poster, međunarodna recenzija, sažetak, stručni)


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Naslov
Evaluation of cap-piercing technology for coagulation testing on Sysmex CS-2500 system

Autori
Komljenović, Sven ; Zrinski Topić, Renata ; Leniček Krleža, Jasna

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Clinical Chemistry and Laboratory Medicine / - Berlin : De Gruyter, 2019, EA60-eA61

Skup
5th EFLM Conference on Preanalytical Phase

Mjesto i datum
Zagreb, Hrvatska, 22-23.03.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Cap-piercing technology ; coagulation ; method comparisson
(cap-piercing technology ; coagulation ; method comparisson)

Sažetak
Background Cap-piercing technology is a mechanism that has emerged in order to improve the laboratory staff safety by reducing exposure to the biological specimen. The aim of the study was to examine whether cap-piercing technology is reliable for routine use since nonreproducible results were previously noticed for coagulation tests, noticeably fibrinogen concentration that was measured by Sysmex® CS-2500 System coagulation analyzer. Materials and Methods Our study collectively used 58 blood samples from pediatric population standardized for coagulation testing which had their Prothrombin time (PT) measured using coagulometric assay (Dade Innovin, Siemens), fibrinogen concentration measured using coagulometric assay (Dade Thrombin, Siemens), D-dimer concentration measured using immunoturbidimetric assay (Innovance D-dimer, Siemens) and/or Protein C activity measured using spectrophotometric assay (Berichrom Protein C, Siemens) from the capped tube and then the decapped tube. Bland-Altman analysis and Passing-Bablok regression analysis have been used to compare results. Results No significant difference has been observed for any of the previously mentioned tests when Bland-Altman analysis (with Westgard's QC rules) has been used: PT had average BIAS = 0.7% (desirable BIAS = 2.0%), fibrinogen had average BIAS = 0.4% (desirable BIAS = 4.8%), Protein C had average BIAS = 0.2% (desirable BIAS = 13.9%) and D-dimer had average BIAS = 0.2% (desirable BIAS = 8.82%). Passing-Bablok regression analysis showed no significant difference for PT (y = [-0.0305 – 0.0000] + [1.0000 – 1.0411] x), Protein C (y = [-2.2598 – 1.1058] + [0.9843 – 1.0217] x) and D-dimer (y = [-0.0249 – 0.0175] + [0.9688 – 1.0235] x). Passing-Bablok regression analysis for fibrinogen showed systematic and proportional differences (y = [0.0087 – 0.0997] + [0.9547 – 0.9935] x). Conclussion We have concluded that cap-piercing technology is acceptable for routine coagulation testing on Sysmex® CS-2500 System.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Klinika za dječje bolesti

Citiraj ovu publikaciju

Komljenović, Sven; Zrinski Topić, Renata; Leniček Krleža, Jasna
Evaluation of cap-piercing technology for coagulation testing on Sysmex CS-2500 system // Clinical Chemistry and Laboratory Medicine
Berlin: De Gruyter, 2019. str. eA60-eA61 (poster, međunarodna recenzija, sažetak, stručni)
Komljenović, S., Zrinski Topić, R. & Leniček Krleža, J. (2019) Evaluation of cap-piercing technology for coagulation testing on Sysmex CS-2500 system. U: Clinical Chemistry and Laboratory Medicine.
@article{article, year = {2019}, pages = {eA60-eA61}, keywords = {cap-piercing technology, coagulation, method comparisson}, title = {Evaluation of cap-piercing technology for coagulation testing on Sysmex CS-2500 system}, keyword = {cap-piercing technology, coagulation, method comparisson}, publisher = {De Gruyter}, publisherplace = {Zagreb, Hrvatska} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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