Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1034689

Nix phosphorylation and dimerization: two mechanisms of mitophagy activation


Marinković, Mija; Šprung, Matilda; Rogov, Vladimir; Dötsch, Volker; Dikic Ivan; Novak, Ivana
Nix phosphorylation and dimerization: two mechanisms of mitophagy activation // FEBS3+ From molecules to living systems
Siofok, Mađarska, 2018. str. 1-1 (poster, nije recenziran, sažetak, znanstveni)


CROSBI ID: 1034689 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Nix phosphorylation and dimerization: two mechanisms of mitophagy activation

Autori
Marinković, Mija ; Šprung, Matilda ; Rogov, Vladimir ; Dötsch, Volker ; Dikic Ivan ; Novak, Ivana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
FEBS3+ From molecules to living systems

Mjesto i datum
Siofok, Mađarska, 02-05.09.2018

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
Mitophagy ; dimerization ; phosphorylation ; NIX

Sažetak
Growing evidences of the function of particular autophagy receptors indicate that most of them are often working together in the same selective autophagy pathway, such as aggrephagy, xenophagy and mitophagy. Several mitophagy receptors have been described such as scAtg32, BNIP3 and Bnip3L/Nix that interact with Atg8/LC3/GABARAP family proteins in LIR-dependent manner and recruit autophagy machinery to damaged mitochondria. This research is focused on Bnip3L/Nix receptor and its regulation. Our current results show that phosphorylation and dimerization of mitophagy receptors Nix and Bnip3 are essential for the initiation of mitochondrial sequestration by autophagic machinery and are involved in mitophagy fine-tuning.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
HRZZ-UIP-2013-11-5246 - Uloga receptora autofagije u selektivnom uklanjanju mitohondrija (AutoMito) (Novak Nakir, Ivana, HRZZ - 2013-11) ( POIROT)

Ustanove:
Prirodoslovno-matematički fakultet, Split,
Medicinski fakultet, Split

Profili:

Avatar Url Ivana Novak (autor)

Avatar Url Matilda Šprung (autor)

Avatar Url Mija Marinković (autor)


Citiraj ovu publikaciju

Marinković, Mija; Šprung, Matilda; Rogov, Vladimir; Dötsch, Volker; Dikic Ivan; Novak, Ivana
Nix phosphorylation and dimerization: two mechanisms of mitophagy activation // FEBS3+ From molecules to living systems
Siofok, Mađarska, 2018. str. 1-1 (poster, nije recenziran, sažetak, znanstveni)
Marinković, M., Šprung, M., Rogov, V., Dötsch, V., Dikic Ivan & Novak, I. (2018) Nix phosphorylation and dimerization: two mechanisms of mitophagy activation. U: FEBS3+ From molecules to living systems.
@article{article, year = {2018}, pages = {1-1}, keywords = {Mitophagy, dimerization, phosphorylation, NIX}, title = {Nix phosphorylation and dimerization: two mechanisms of mitophagy activation}, keyword = {Mitophagy, dimerization, phosphorylation, NIX}, publisherplace = {Siofok, Ma\djarska} }
@article{article, year = {2018}, pages = {1-1}, keywords = {Mitophagy, dimerization, phosphorylation, NIX}, title = {Nix phosphorylation and dimerization: two mechanisms of mitophagy activation}, keyword = {Mitophagy, dimerization, phosphorylation, NIX}, publisherplace = {Siofok, Ma\djarska} }




Contrast
Increase Font
Decrease Font
Dyslexic Font