Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1033929

Quantitative PCR Technology in Chimerism Monitoring After Hsct ‐ One Centre Experience


Štingl Janković, Katarina; Maskalan, Marija; Burek Kamenarić, Marija; Žunec, Renata; Duraković, Nadira; Serventi‐Seiwerth, Ranka; Vrhovac, Radovan; Grubić, Zorana
Quantitative PCR Technology in Chimerism Monitoring After Hsct ‐ One Centre Experience // HLA, 94 (2019), 31577854, 10 doi:10.1111/tan.13707 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1033929 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Quantitative PCR Technology in Chimerism Monitoring After Hsct ‐ One Centre Experience

Autori
Štingl Janković, Katarina ; Maskalan, Marija ; Burek Kamenarić, Marija ; Žunec, Renata ; Duraković, Nadira ; Serventi‐Seiwerth, Ranka ; Vrhovac, Radovan ; Grubić, Zorana

Izvornik
HLA (2059-2310) 94 (2019); 31577854, 10

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
HSCT ; chimerism ; qPCR

Sažetak
Chimerism status evaluation is a routine test performed in post-HSCT period. Aim of the study was to evaluate a qPCR method (GenDx, Utrecht, the Netherlands) applicability for this purpose. Study included 74 recipient/donor pairs tested for informative markers: median of four and six informative markers was found for patients (related and unrelated donor, respectively). Higher sensitivity of qPCR method was confirmed by analysis of recipient post-HSCT samples (N = 800) among which microchimerism (0.1-1% recipient DNA) was detected in 21.8% of cases. The ability to detect less than 1% of minor population, as opposed to the Short Tandem Repeat (STR) method for which 1% is the limit, translated into earlier identification of a disease relapse for four patients in our study sample.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Klinički bolnički centar Zagreb

doi

Citiraj ovu publikaciju

Štingl Janković, Katarina; Maskalan, Marija; Burek Kamenarić, Marija; Žunec, Renata; Duraković, Nadira; Serventi‐Seiwerth, Ranka; Vrhovac, Radovan; Grubić, Zorana
Quantitative PCR Technology in Chimerism Monitoring After Hsct ‐ One Centre Experience // HLA, 94 (2019), 31577854, 10 doi:10.1111/tan.13707 (međunarodna recenzija, članak, znanstveni)
Štingl Janković, K., Maskalan, M., Burek Kamenarić, M., Žunec, R., Duraković, N., Serventi‐Seiwerth, R., Vrhovac, R. & Grubić, Z. (2019) Quantitative PCR Technology in Chimerism Monitoring After Hsct ‐ One Centre Experience. HLA, 94, 31577854, 10 doi:10.1111/tan.13707.
@article{article, year = {2019}, pages = {10}, DOI = {10.1111/tan.13707}, chapter = {31577854}, keywords = {HSCT, chimerism, qPCR}, journal = {HLA}, doi = {10.1111/tan.13707}, volume = {94}, issn = {2059-2310}, title = {Quantitative PCR Technology in Chimerism Monitoring After Hsct ‐ One Centre Experience}, keyword = {HSCT, chimerism, qPCR}, chapternumber = {31577854} }
@article{article, year = {2019}, pages = {10}, DOI = {10.1111/tan.13707}, chapter = {31577854}, keywords = {HSCT, chimerism, qPCR}, journal = {HLA}, doi = {10.1111/tan.13707}, volume = {94}, issn = {2059-2310}, title = {Quantitative PCR Technology in Chimerism Monitoring After Hsct ‐ One Centre Experience}, keyword = {HSCT, chimerism, qPCR}, chapternumber = {31577854} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font