Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1033834

Biomarkers in schizophrenia: protocol for follow-up study of patients with first episode psychosis


Makarić, Porin; Bošnjak Kuharić, Dina; Kekin, Ivana; Madžarac, Zoran; Savić, Aleksandar; Silić, Ante; Ostojić, Draženka; Šagud, Marina; Brečić, Petrana; Jukić, Vlado; Rojnić Kuzman, Martina
Biomarkers in schizophrenia: protocol for follow-up study of patients with first episode psychosis // European Psychiatry / Fiorillo, Andrea (ur.).
Varšava: Elsevier, 2019. str. S716-S717 (poster, međunarodna recenzija, sažetak, znanstveni)


CROSBI ID: 1033834 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Biomarkers in schizophrenia: protocol for follow-up study of patients with first episode psychosis

Autori
Makarić, Porin ; Bošnjak Kuharić, Dina ; Kekin, Ivana ; Madžarac, Zoran ; Savić, Aleksandar ; Silić, Ante ; Ostojić, Draženka ; Šagud, Marina ; Brečić, Petrana ; Jukić, Vlado ; Rojnić Kuzman, Martina

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
European Psychiatry / Fiorillo, Andrea - Varšava : Elsevier, 2019, S716-S717

Skup
27th European Congress of Psychiatry

Mjesto i datum
Varšava, Poljska, 06-09.03.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
schizophrenia ; first episode psychosis ; biological markers ; neurocognition ; TCD ; SPECT ; stress ; cortisole

Sažetak
Introduction: Huge efforts have been made to identify a biological correlate of schizophrenia in order to confirm the diagnosis and predict the outcome, but there are still no reliable biological markers. Our aim was to investigate possible clinical, functional and structural biomarkers of schizophrenia which are present during the first episode and monitor their changes during time. Methods: We have conducted a longitudinal study in patients with first episode of psychosis (FEP) and healthy controls (HC). Assessment included clinical interview, sociodemographic questionnaire, psychiatric rating scales and questionnaires and specific additional assessments that were divided into three work packages (WP). The first WP included neurocognitive and facial emotional recognition assessment with adequate tests, the second WP assessment of cerebral blood flow velocity with transcranial Doppler ultrasound, and the third WP assessment of regional cerebral perfusion with single photon emission computed tomography. Patients were assessed at baseline and after 18-month follow-up and HC at one time point. Results: We shall: 1. analyse the differences between FEP and HC, 2. analyse the changes during the course of illness from baseline to the end of study, 3. perform an exploratory analysis combining the results of different tests in order to identify potential disease phenotypes and their impact on treatment outcome. Conclusion: Identifying possible biological markers could help us in better understanding of illness and its course, as well as to tailor its treatment on individual basis.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
UIP-2014-09-1245

Ustanove
Medicinski fakultet, Zagreb,
Klinika za psihijatriju Vrapče,
KBC "Sestre Milosrdnice",
Klinički bolnički centar Zagreb

Citiraj ovu publikaciju

Makarić, Porin; Bošnjak Kuharić, Dina; Kekin, Ivana; Madžarac, Zoran; Savić, Aleksandar; Silić, Ante; Ostojić, Draženka; Šagud, Marina; Brečić, Petrana; Jukić, Vlado; Rojnić Kuzman, Martina
Biomarkers in schizophrenia: protocol for follow-up study of patients with first episode psychosis // European Psychiatry / Fiorillo, Andrea (ur.).
Varšava: Elsevier, 2019. str. S716-S717 (poster, međunarodna recenzija, sažetak, znanstveni)
Makarić, P., Bošnjak Kuharić, D., Kekin, I., Madžarac, Z., Savić, A., Silić, A., Ostojić, D., Šagud, M., Brečić, P., Jukić, V. & Rojnić Kuzman, M. (2019) Biomarkers in schizophrenia: protocol for follow-up study of patients with first episode psychosis. U: Fiorillo, A. (ur.)European Psychiatry.
@article{article, editor = {Fiorillo, A.}, year = {2019}, pages = {S716-S717}, keywords = {schizophrenia, first episode psychosis, biological markers, neurocognition, TCD, SPECT, stress, cortisole}, title = {Biomarkers in schizophrenia: protocol for follow-up study of patients with first episode psychosis}, keyword = {schizophrenia, first episode psychosis, biological markers, neurocognition, TCD, SPECT, stress, cortisole}, publisher = {Elsevier}, publisherplace = {Var\v{s}ava, Poljska} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • MEDLINE