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Pregled bibliografske jedinice broj: 1033133

Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers


(College of Medicine, QU Health, Qatar University, Doha, Qatar) Karin-Kujundzic, Valentina; Sola, Ida Marija; Predavec, Nina; Potkonjak, Anamarija; Somen, Ema; Mioc, Pavao; Serman, Alan; Vranic, Semir; Serman, Ljiljana
Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers // Cells, 8 (2019), 11; 1459, 37 doi:10.3390/cells8111459 (međunarodna recenzija, pregledni rad, znanstveni)


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Naslov
Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers

Autori
Karin-Kujundzic, Valentina ; Sola, Ida Marija ; Predavec, Nina ; Potkonjak, Anamarija ; Somen, Ema ; Mioc, Pavao ; Serman, Alan ; Vranic, Semir ; Serman, Ljiljana

Kolaboracija
College of Medicine, QU Health, Qatar University, Doha, Qatar

Izvornik
Cells (2073-4409) 8 (2019), 11; 1459, 37

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
Cell-free DNA ; Cell-free fetal DNA ; Cell-free tumor DNA ; Extracellular vesicles ; Exosomes ; MicroRNA
(cell-free DNA ; cell-free fetal DNA ; cell-free tumor DNA ; extracellular vesicles ; exosomes ; microRNA)

Sažetak
As the majority of cancers and gestational diseases are prognostically stage- and grade- dependent, the ultimate goal of ongoing studies in precision medicine is to provide early and timely diagnosis of such disorders. These studies have enabled the development of various new diagnostic biomarkers, such as free circulating nucleic acids, and detection of their epigenetic changes. Recently, extracellular vesicles including exosomes, microvesicles, oncosomes, and apoptotic bodies have been recognized as powerful diagnostic tools. Extracellular vesicles carry specific proteins, lipids, DNAs, mRNAs, and miRNAs of the cells that produced them, thus reflecting the function of these cells. It is believed that exosomes, in particular, may be the optimal biomarkers of pathological pregnancies and cancers, especially those that are frequently diagnosed at an advanced stage, such as ovarian cancer. In the present review, we survey and critically appraise novel epigenetic biomarkers related to free circulating nucleic acids and extracellular vesicles, focusing especially on their status in trophoblasts (pregnancy) and neoplastic cells (cancers).

Izvorni jezik
Engleski



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Zagreb

Poveznice na cjeloviti tekst rada:

Pristup cjelovitom tekstu rada doi www.mdpi.com

Citiraj ovu publikaciju:

(College of Medicine, QU Health, Qatar University, Doha, Qatar) Karin-Kujundzic, Valentina; Sola, Ida Marija; Predavec, Nina; Potkonjak, Anamarija; Somen, Ema; Mioc, Pavao; Serman, Alan; Vranic, Semir; Serman, Ljiljana
Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers // Cells, 8 (2019), 11; 1459, 37 doi:10.3390/cells8111459 (međunarodna recenzija, pregledni rad, znanstveni)
(College of Medicine, QU Health, Qatar University, Doha, Qatar) (College of Medicine, QU Health, Qatar University, Doha, Qatar) Karin-Kujundzic, Valentina, Sola, I., Predavec, N., Potkonjak, A., Somen, E., Mioc, P., Serman, A., Vranic, S. & Serman, L. (2019) Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers. Cells, 8 (11), 1459, 37 doi:10.3390/cells8111459.
@article{article, author = {Karin-Kujundzic, Valentina and Sola, Ida Marija and Predavec, Nina and Potkonjak, Anamarija and Somen, Ema and Mioc, Pavao and Serman, Alan and Vranic, Semir and Serman, Ljiljana}, year = {2019}, pages = {37}, DOI = {10.3390/cells8111459}, chapter = {1459}, keywords = {Cell-free DNA, Cell-free fetal DNA, Cell-free tumor DNA, Extracellular vesicles, Exosomes, MicroRNA}, journal = {Cells}, doi = {10.3390/cells8111459}, volume = {8}, number = {11}, issn = {2073-4409}, title = {Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers}, keyword = {Cell-free DNA, Cell-free fetal DNA, Cell-free tumor DNA, Extracellular vesicles, Exosomes, MicroRNA}, chapternumber = {1459} }
@article{article, author = {Karin-Kujundzic, Valentina and Sola, Ida Marija and Predavec, Nina and Potkonjak, Anamarija and Somen, Ema and Mioc, Pavao and Serman, Alan and Vranic, Semir and Serman, Ljiljana}, year = {2019}, pages = {37}, DOI = {10.3390/cells8111459}, chapter = {1459}, keywords = {cell-free DNA, cell-free fetal DNA, cell-free tumor DNA, extracellular vesicles, exosomes, microRNA}, journal = {Cells}, doi = {10.3390/cells8111459}, volume = {8}, number = {11}, issn = {2073-4409}, title = {Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers}, keyword = {cell-free DNA, cell-free fetal DNA, cell-free tumor DNA, extracellular vesicles, exosomes, microRNA}, chapternumber = {1459} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


Citati:





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