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Pregled bibliografske jedinice broj: 1032218

NEUROCOGNITIVE PROFILES OF PATIENTS WITH THE FIRST EPISODE OF PSYCHOSIS AND SCHIZOPHRENIA DO NOT DIFFER QUALITATIVELY: A NESTED CROSS-SECTIONAL STUDY


Bošnjak Kuharić, Dina; Makarić, Porin; Kekin, Ivana; Bajić, Žarko; Živković, Maja; Savić, Aleksandar; Ostojić, Draženka; Jukić, Vlado; Rojnić Kuzman, Martina
NEUROCOGNITIVE PROFILES OF PATIENTS WITH THE FIRST EPISODE OF PSYCHOSIS AND SCHIZOPHRENIA DO NOT DIFFER QUALITATIVELY: A NESTED CROSS-SECTIONAL STUDY // Psychiatria Danubina, 31 (2019), 1; 43-53 doi:10.24869/psyd.2019.43 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1032218 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
NEUROCOGNITIVE PROFILES OF PATIENTS WITH THE FIRST EPISODE OF PSYCHOSIS AND SCHIZOPHRENIA DO NOT DIFFER QUALITATIVELY: A NESTED CROSS-SECTIONAL STUDY

Autori
Bošnjak Kuharić, Dina ; Makarić, Porin ; Kekin, Ivana ; Bajić, Žarko ; Živković, Maja ; Savić, Aleksandar ; Ostojić, Draženka ; Jukić, Vlado ; Rojnić Kuzman, Martina

Izvornik
Psychiatria Danubina (0353-5053) 31 (2019), 1; 43-53

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
neurocognitive impairment ; neurocognitive profile ; psychotic disorders ; first-episode psychosis ; schizophrenia

Sažetak
Background: The aim of study was to analyze neurocognitive profiles in patients with first-episode psychosis (FEP) and patients with schizophrenia (SCH), and their correlations with other clinical features. Subjects and methods: We performed a multicentric cross sectional study including 100 FEP and 100 SCH recruited from three Croatian hospitals during 2015-2017. Assessment included a set of neurocognitive tests, psychiatric scales and self-reporting questionnaires. The main analysis was done by multigroup latent profile analysis. Results: Multigroup latent profile analysis resulted in three structurally equivalent neurocognitive profiles ("Best", "Medium", "Worst"), with differences in the severity of neurocognitive deficits measured with successfulness in solving domain specific tasks. The "Best" profile was statistically significantly more prevalent in FEP and "Worst" profile in the SCH. Negative symptom score was the highest in patients with the "Worst" profile and the lowest among those with the "Best" profiles. Conclusions: Differences in neurocognitive profiles between FEP and SCH appear to be quantitative rather than qualitative nature, possibly reflecting a specific trait of illness that may progress over time. Defining neurocognitive profiles from the first episode of psychosis could help in tailoring individualized treatment options with focus on neurocognitive and negative symptoms and possible influence on patients' overall clinical outcome.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
UIP-2014-09-1245

Ustanove
Medicinski fakultet, Zagreb,
Klinika za psihijatriju Vrapče,
Klinički bolnički centar Zagreb

Citiraj ovu publikaciju

Bošnjak Kuharić, Dina; Makarić, Porin; Kekin, Ivana; Bajić, Žarko; Živković, Maja; Savić, Aleksandar; Ostojić, Draženka; Jukić, Vlado; Rojnić Kuzman, Martina
NEUROCOGNITIVE PROFILES OF PATIENTS WITH THE FIRST EPISODE OF PSYCHOSIS AND SCHIZOPHRENIA DO NOT DIFFER QUALITATIVELY: A NESTED CROSS-SECTIONAL STUDY // Psychiatria Danubina, 31 (2019), 1; 43-53 doi:10.24869/psyd.2019.43 (međunarodna recenzija, članak, znanstveni)
Bošnjak Kuharić, D., Makarić, P., Kekin, I., Bajić, Ž., Živković, M., Savić, A., Ostojić, D., Jukić, V. & Rojnić Kuzman, M. (2019) NEUROCOGNITIVE PROFILES OF PATIENTS WITH THE FIRST EPISODE OF PSYCHOSIS AND SCHIZOPHRENIA DO NOT DIFFER QUALITATIVELY: A NESTED CROSS-SECTIONAL STUDY. Psychiatria Danubina, 31 (1), 43-53 doi:10.24869/psyd.2019.43.
@article{article, year = {2019}, pages = {43-53}, DOI = {10.24869/psyd.2019.43}, keywords = {neurocognitive impairment, neurocognitive profile, psychotic disorders, first-episode psychosis, schizophrenia}, journal = {Psychiatria Danubina}, doi = {10.24869/psyd.2019.43}, volume = {31}, number = {1}, issn = {0353-5053}, title = {NEUROCOGNITIVE PROFILES OF PATIENTS WITH THE FIRST EPISODE OF PSYCHOSIS AND SCHIZOPHRENIA DO NOT DIFFER QUALITATIVELY: A NESTED CROSS-SECTIONAL STUDY}, keyword = {neurocognitive impairment, neurocognitive profile, psychotic disorders, first-episode psychosis, schizophrenia} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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