Gestational diabetes and pregnancy outcome – do we have right diagnostic criteria? (CROSBI ID 270762)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Tomić, Vajdana ; Petrović, Oleg ; Crnčević Orlić, Željka ; Mandić, Vjekoslav
engleski
Gestational diabetes and pregnancy outcome – do we have right diagnostic criteria?
Objective: To determine thresholds of maternal glycemia at which specific adverse pregnancy outcomes occur in high-risk population. Methods: A total of 1002 pregnant women with risk factors for gestational diabetes mellitus (GDM) underwent an originally modified glucose tolerance test (OGTT) with 75 g of glucose. Information on OGTT results and pregnancy outcomes were collected from database and medical records. Results: Large for gestational age (LGA) newborn, infant’s stay in the neonatal intensive care unit (NICU) >24 h, neonatal hyperbilirubinemia and cesarean section due to cephalopelvic disproportion were identified as specific GDM adverse outcomes. In the study group of participants with one or more specific GDM adverse outcomes, mean glycemic values during the modified OGTT (4.2 ± 1.0 mmol/L at 0 min, 6.8 ± 1.7 mmol/L at 30 min, 7.9 ± 2.1 mmol/L at 60 min, 7.7 ± 2.3 mmol/L at 90 min and 7.5 ± 2.3 mmol/L at 120 min) according to Student’s t-test for independent samples were significantly higher than mean glycemic values in the control group of participants without specific adverse outcomes (p < 0.001, p = 0.02, p < 0.001, p < 0.001, p < 0.001). Conclusion: This study provides additional data that support the acceptance of the newly recommended outcome- based GDM diagnostic criteria.
diagnostic criteria ; gestational diabetes ; glucose tolerance test ; pregnancy outcome
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Podaci o izdanju
26 (9)
2013.
854-859
objavljeno
1476-7058
10.3109/14767058.2013.776530
Povezanost rada
Kliničke medicinske znanosti