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Pregled bibliografske jedinice broj: 1031398

Role of ganglioside GM1 expression in T lymphocytes membranes in cervical cancer development


Danolić, Damir; Heffer, Marija; Wagner, Jasenka; Škrlec, Ivana; Alvir, Ilija; Mamić, Ivica; Šušnjar, Lucija; Marcelić, Luka; Bečejac, Tomislav; Puljiz, Mario
Role of ganglioside GM1 expression in T lymphocytes membranes in cervical cancer development // International Journal of Gynecologic Cancer / Ramirez, Pedro T (ur.).
Hoboken, USA: BMJ, 2019. EP280, 1 doi:10.1136/ijgc-2019-ESGO.341 (poster, međunarodna recenzija, sažetak, ostalo)


CROSBI ID: 1031398 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Role of ganglioside GM1 expression in T lymphocytes membranes in cervical cancer development

Autori
Danolić, Damir ; Heffer, Marija ; Wagner, Jasenka ; Škrlec, Ivana ; Alvir, Ilija ; Mamić, Ivica ; Šušnjar, Lucija ; Marcelić, Luka ; Bečejac, Tomislav ; Puljiz, Mario

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
International Journal of Gynecologic Cancer / Ramirez, Pedro T - Hoboken, USA : BMJ, 2019

Skup
21th International Meeting of the European Society of Gynaecological Oncology

Mjesto i datum
Atena, Grčka, 2-5.11.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Cervical cancer ; ganglioside GM1 ; flow cytometry

Sažetak
Introduction/Background Cervical cancer is worldwide the second most common cancer in women. Immune response appears to be a key determinant in controlling human papilloma virus (HPV) infection. Cell mediated immunity plays a significiant role in progression or regression of neoplastic cervical lesions. Lipid rafts have essential role in T lymphocite activation. Gangliosides play an important role in the formation and stabilization of specific cell lipid membrane domains. This study aims to determine whether ganglioside GM1 expressions in T cell membrane represent risk factor for cervical cancer. Methodology In total, 20 women participated in our study. Peripheral blood samples were obtained from 10 cervical cancer patients and 10 healthy controls at University Hospital for Tumors, Zagreb, Croatia. A 3 mL sample of venous blood was collected from each subject into a test tube containing EDTA as anticoagulant. For T cell subtypes isolation we used Anti CD4 Phycoerythrin antibody and Anti CD8 Peridinin Chlorophyll Protein Complex antibody. Ganglioside GM1 expression in T lymphocytes membranes was analyzed using double labeling antibodies on ganglioside GM1. Results We have not found difference in ganglioside GM1 expression in T lymphocytes membranes between the two groups. Conclusion The present study did not show association of ganglioside GM1 expression in T lymphocytes membranes with cervical cancer development.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
KBC "Sestre Milosrdnice",
Klinički bolnički centar Zagreb,
Medicinski fakultet, Osijek,
Fakultet za dentalnu medicinu i zdravstvo, Osijek

Profili:

Avatar Url Jasenka Wagner (autor)

Avatar Url Ivana Škrlec (autor)

Avatar Url Marija Heffer (autor)

Avatar Url Ilija Alvir (autor)

Avatar Url Mario Puljiz (autor)

Avatar Url Tomislav Bečejac (autor)

Poveznice na cjeloviti tekst rada:

doi ijgc.bmj.com

Citiraj ovu publikaciju:

Danolić, Damir; Heffer, Marija; Wagner, Jasenka; Škrlec, Ivana; Alvir, Ilija; Mamić, Ivica; Šušnjar, Lucija; Marcelić, Luka; Bečejac, Tomislav; Puljiz, Mario
Role of ganglioside GM1 expression in T lymphocytes membranes in cervical cancer development // International Journal of Gynecologic Cancer / Ramirez, Pedro T (ur.).
Hoboken, USA: BMJ, 2019. EP280, 1 doi:10.1136/ijgc-2019-ESGO.341 (poster, međunarodna recenzija, sažetak, ostalo)
Danolić, D., Heffer, M., Wagner, J., Škrlec, I., Alvir, I., Mamić, I., Šušnjar, L., Marcelić, L., Bečejac, T. & Puljiz, M. (2019) Role of ganglioside GM1 expression in T lymphocytes membranes in cervical cancer development. U: Ramirez, P. (ur.)International Journal of Gynecologic Cancer doi:10.1136/ijgc-2019-ESGO.341.
@article{article, editor = {Ramirez, P.}, year = {2019}, pages = {1}, DOI = {10.1136/ijgc-2019-ESGO.341}, chapter = {EP280}, keywords = {Cervical cancer, ganglioside GM1, flow cytometry}, doi = {10.1136/ijgc-2019-ESGO.341}, title = {Role of ganglioside GM1 expression in T lymphocytes membranes in cervical cancer development}, keyword = {Cervical cancer, ganglioside GM1, flow cytometry}, publisher = {BMJ}, publisherplace = {Atena, Gr\v{c}ka}, chapternumber = {EP280} }
@article{article, editor = {Ramirez, P.}, year = {2019}, pages = {1}, DOI = {10.1136/ijgc-2019-ESGO.341}, chapter = {EP280}, keywords = {Cervical cancer, ganglioside GM1, flow cytometry}, doi = {10.1136/ijgc-2019-ESGO.341}, title = {Role of ganglioside GM1 expression in T lymphocytes membranes in cervical cancer development}, keyword = {Cervical cancer, ganglioside GM1, flow cytometry}, publisher = {BMJ}, publisherplace = {Atena, Gr\v{c}ka}, chapternumber = {EP280} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati:





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