engleski

Morphological properties of the epithelial tissue

Properties of packing systems on various interfaces are of vital interest for many reasons like amorphous materials, liquids, 3D printing and in life sciences. We investigate morphology of randomly packed ellipses through whole phase-space of packing fractions and ellipse aspect ratios. Furthermore, we compare properties of random packings to the packings of MDCK II epithelial tissue nuclei on their interfaces. Cell nuclei can be approximated with ellipses and the Voronoi tesselation generated by those ellipses coincides well with the cell membranes. The comparison of tissue cells and random packing is done by studying the probability distributions of chosen morphological measures calculated from the cells. We find that randomly packed ellipses reproduce the morphology of the tissue well at the low cell density. At high cell density we observe more regular structure of the tissue an we see the deviations of the random model from the cell tissue.

tissue modeling ; random packings ; Voronoi diagram

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