engleski

Weight Loss Biochemistry

Through the evolution human body has been programed to store the excess of energy in two different pools, glycogen and triacylglicerols. While the first one is less prone to the changes in the evolutionary programmed storage capability, the latter one has almost unlimited capability to be stored, not only to the evolutionary created safe storage “warehouse” (adipocytes), but also to other cells of the human body when fatty acid spillover occurs. While this evolutionary inheritance worked more or less well during the ages, where the excess of available foods has been stored in metabolic pools in periods of food abundance, and than used for energy input in times of food shortages, the development of modern human societies, characterized with the high level of industrialization and automatization led to the disruption of this equilibrium toward the former one. Nowadays, modern human societies has been challenged with the continuous excess of available foods and decreased physical activity, what subsequently leads to the increased level of overweight and obesity among population. Therefore, the need for social programming of human societies toward healthy lifestyle, including increase in physical activity and changes in dietary habits, is inevitable. In this respect, the present lecture will give overview of the current knowledge of the effect of physical activity, oftenly used reduction diets, and their combined effects on weight loss from the biochemical point of view.

biochemistry ; diets ; obesity ; owerweight ; weight loss

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