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Production of green note component on a microscale – From idea to integrated systems

In comparison with macro level, batch production processes development of continuous, micro level production processes presents a certain challenge since a lot of new physical phenomena emerge. Different heat and mass transport phenomena, different diffusion time, enhanced surface roughness impact, different flow profiles etc. are just some of the challenges that have to be overcome in order to develop a functional production system on a microscale. As a case study for this statement production of hexanal has been investigated. Different experimental approaches for production in a microreactor were necessary in order to transfer already established microscale batch production. While “one pot” principle was working perfectly for batch production, it was necessary to develop an integrated system with several connected microchips for successful and effective hexanal production on a microscale. In this paper, basic steps that led from idea to integrated system of hexanal production on a microscale are demonstrated.

hexanol oxidation, hexanal, microreactor, alcohol dehydrogenase, coenzyme regeneration, immobilization

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