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Pregled bibliografske jedinice broj: 1027618

Solid-state study of the host-guest complexes of beta-cyclodextrin and ferrocene thymine conjugates


Frkanec, Leo; Gazdek, Nika; Halasz, Ivan; Maračić, Silvija; Lapić, Jasmina; Raić-Malić, Silvana; Djaković, Senka; Frkanec, Ruža
Solid-state study of the host-guest complexes of beta-cyclodextrin and ferrocene thymine conjugates // Solid-State Science & Research 2019, book of abstracts / Biliškov, Nikola (ur.).
Zagreb: Institut Ruđer Bošković, 2019. str. 102-102 (poster, međunarodna recenzija, sažetak, znanstveni)


CROSBI ID: 1027618 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Solid-state study of the host-guest complexes of beta-cyclodextrin and ferrocene thymine conjugates

Autori
Frkanec, Leo ; Gazdek, Nika ; Halasz, Ivan ; Maračić, Silvija ; Lapić, Jasmina ; Raić-Malić, Silvana ; Djaković, Senka ; Frkanec, Ruža

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Solid-State Science & Research 2019, book of abstracts / Biliškov, Nikola - Zagreb : Institut Ruđer Bošković, 2019, 102-102

ISBN
978-953-7941-32-1

Skup
Solid-State Science and Research

Mjesto i datum
Zagreb, Hrvatska, 27-29.06.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Ferocen ; Mehanokemija ; Beta-cyclodekstrin
(Ferrocene ; Mechanochemistry ; Beta-cyclodextrin)

Sažetak
It has been recently shown that N‐alkylated ferrocene quinoline conjugates exhibited inhibitory effects on selected tumor cell lines. Similar biological activity has been demonstrated by ferrocene thymine conjugates. However, their application is limited, due to the high lipophilicity of these compounds. Therefore, to solve this obstacle inclusion complexes with cyclodextrin have proved to be useful because they allow better solubility in water, and thus better biodistribution and pharmacokinetic properties of some drugs. The formation of inclusion complex of bis-ferrocene thymine conjugates and beta-cyclodextrin was carried out by milling. Host-guest complexation in the solid state was studied and characterized by NMR spectroscopy and X-ray powder diffraction.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekti:
HRZZ-IP-2018-01-6910 - Sinteza supramolekulskih samo-udruženih nanostruktura za izgradnju naprednih funkcionalnih materijala (SUPeRNANO) (Frkanec, Leo, HRZZ - 2018-01) ( POIROT)

Ustanove:
Prehrambeno-biotehnološki fakultet, Zagreb,
Institut "Ruđer Bošković", Zagreb,
Fakultet kemijskog inženjerstva i tehnologije, Zagreb,
Sveučilište u Zagrebu

Citiraj ovu publikaciju

Frkanec, Leo; Gazdek, Nika; Halasz, Ivan; Maračić, Silvija; Lapić, Jasmina; Raić-Malić, Silvana; Djaković, Senka; Frkanec, Ruža
Solid-state study of the host-guest complexes of beta-cyclodextrin and ferrocene thymine conjugates // Solid-State Science & Research 2019, book of abstracts / Biliškov, Nikola (ur.).
Zagreb: Institut Ruđer Bošković, 2019. str. 102-102 (poster, međunarodna recenzija, sažetak, znanstveni)
Frkanec, L., Gazdek, N., Halasz, I., Maračić, S., Lapić, J., Raić-Malić, S., Djaković, S. & Frkanec, R. (2019) Solid-state study of the host-guest complexes of beta-cyclodextrin and ferrocene thymine conjugates. U: Biliškov, N. (ur.)Solid-State Science & Research 2019, book of abstracts.
@article{article, editor = {Bili\v{s}kov, N.}, year = {2019}, pages = {102-102}, keywords = {Ferocen, Mehanokemija, Beta-cyclodekstrin}, isbn = {978-953-7941-32-1}, title = {Solid-state study of the host-guest complexes of beta-cyclodextrin and ferrocene thymine conjugates}, keyword = {Ferocen, Mehanokemija, Beta-cyclodekstrin}, publisher = {Institut Ru\djer Bo\v{s}kovi\'{c}}, publisherplace = {Zagreb, Hrvatska} }
@article{article, editor = {Bili\v{s}kov, N.}, year = {2019}, pages = {102-102}, keywords = {Ferrocene, Mechanochemistry, Beta-cyclodextrin}, isbn = {978-953-7941-32-1}, title = {Solid-state study of the host-guest complexes of beta-cyclodextrin and ferrocene thymine conjugates}, keyword = {Ferrocene, Mechanochemistry, Beta-cyclodextrin}, publisher = {Institut Ru\djer Bo\v{s}kovi\'{c}}, publisherplace = {Zagreb, Hrvatska} }




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