engleski

Metaplasticity protocol in cognitive training with tDCS

Transcranial direct current stimulation (tDCS) is a relatively new addition to cognitive enhancement procedures, yielding various outcomes. Recently, metaplasticity protocol has been proposed to heighten the training effects. Metaplasticity reffers to activity-dependent changes in neural functions that modulate subsequent synaptic plasticity. The aim of this study was to verify the effectiveness of a combination of tDCS and cognitive training within metaplasticity research design. Thirty one healthy young adults were randomly assigned to either treatment or active control (sham) group. The design included an 8-session training in which equal protocol, differing only in tDCS/sham stimulation, was used for both group (n-back + 5min pause + (n- back+tDCS/sham)), with pretest, postetest and followup at 5 months. Repeated measures ANOVA did not find statistically significant interactions between groups and measurement points for the n-back tasks, forward and backward span, symmetry span, oddball and the bivalent shape task.

metaplasticity, transcranial direct current stimulation, cognitive training

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