engleski

Influence of peripheral electromagnetic solenoid-type vibration on motor cortical excitability: a navigated transcranial magnetic stimulation study

Objectives: Much effort has previously been put towards investigating motor cortical excitability by applying peripheral afferent stimuli in the form of electrical stimulation to the nerves or vibration of the hand muscles. The aim of the present study was to investigate cortical motor excitability in the context of peripheral cutaneous vibration input to the finger. Materials and methods: 11 healthy subjects underwent a conditioning-test (CT) protocol with peripheral vibration of the index finger serving as conditioning, and TMS to M1 serving as test stimulus. Vibration and TMS were separated by randomized inter-stimulus intervals (ISIs) in the range 5-500 ms. Resulting motor evoked potentials (MEPs) were recorded with EMG from the abductor pollicis brevis (APB) muscle, and statistical analysis was performed for its amplitude and latency. Results: Statistically significant suppression of MEP amplitudes in the upper extremity muscle were proven for the ISIs 200, 300, and 400 ms. Conclusion: These findings of suppression of the MEP response at long ISIs are consistent with cortical excitability alterations suggested to result from sensorimotor integration processes following arrival of the afferent sensory volley to the motor cortices.

evoked potentials, motor ; vibration ; transcranial magnetic stimulation ; fingers ; muscles ; motor cortex

nije evidentirano