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Pregled bibliografske jedinice broj: 102033

Interferon-alpha and ribavirin treatment in patients with chronic hepatitis C and normal aminotransferase values


Pavić, Tajana; Duvnjak, Marko; Virović Lucija
Interferon-alpha and ribavirin treatment in patients with chronic hepatitis C and normal aminotransferase values // Acta medica Croatica / Knežević, Stojan ; Duvnjak, Marko ; Beritić-Stahuljak, Dunja (ur.).
Zagreb: Akademija medicinskih znanosti Hrvatske, 2001. (predavanje, međunarodna recenzija, sažetak, stručni)


CROSBI ID: 102033 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Interferon-alpha and ribavirin treatment in patients with chronic hepatitis C and normal aminotransferase values

Autori
Pavić, Tajana ; Duvnjak, Marko ; Virović Lucija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Acta medica Croatica / Knežević, Stojan ; Duvnjak, Marko ; Beritić-Stahuljak, Dunja - Zagreb : Akademija medicinskih znanosti Hrvatske, 2001

Skup
3. kongres Hrvatskog gastroenterološkog društva s međunarodnim sudjelovanjem

Mjesto i datum
Zagreb, Hrvatska, 23-26.09.2001

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
chronic hepatitis C; treatment; interferon-alpha; ribavirin; normal aminotransferase values

Sažetak
Aim: to evaluate the efficacy of combination therapy with interferon-alpha (IFN-alpha) an ribavirin in patients with chronic hepatitis C and normal aminotransferase values. Patients and methods: 12 HCV RNA positive patients (7 males and 5 females, mean age 38, 1 years) with normal or near-normal aminotransferase values on three consecutive occasions and histologically mild disease were included in the study. During the induction period of 4 weeks they received 5 MU IFN-alfa 2b and ribavirin 1000 mg daily. Following 44 weeks they received 3 MU IFN-alfa 2b thrice weekly with ribavirin 1000 mg daily. Serum HCV RNA was tested every three months during treatment, at the end of therapy (end-of-treatment response) and 6 months afterwards (sustained virological response). Results: 7 of 12 patients (58%) cleared the virus at the end of therapy and 5 of 12 (42%) showed sustained virological response. No significant elevation of aminotransferase values was detected during IFN therapy.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
134008

Ustanove:
KBC "Sestre Milosrdnice"

Profili:

Avatar Url Marko Duvnjak (autor)

Avatar Url Lucija Virović Jukić (autor)


Citiraj ovu publikaciju:

Pavić, Tajana; Duvnjak, Marko; Virović Lucija
Interferon-alpha and ribavirin treatment in patients with chronic hepatitis C and normal aminotransferase values // Acta medica Croatica / Knežević, Stojan ; Duvnjak, Marko ; Beritić-Stahuljak, Dunja (ur.).
Zagreb: Akademija medicinskih znanosti Hrvatske, 2001. (predavanje, međunarodna recenzija, sažetak, stručni)
Pavić, T., Duvnjak, M. & Virović Lucija (2001) Interferon-alpha and ribavirin treatment in patients with chronic hepatitis C and normal aminotransferase values. U: Knežević, S., Duvnjak, M. & Beritić-Stahuljak, D. (ur.)Acta medica Croatica.
@article{article, author = {Pavi\'{c}, Tajana and Duvnjak, Marko}, year = {2001}, pages = {110}, keywords = {chronic hepatitis C, treatment, interferon-alpha, ribavirin, normal aminotransferase values}, title = {Interferon-alpha and ribavirin treatment in patients with chronic hepatitis C and normal aminotransferase values}, keyword = {chronic hepatitis C, treatment, interferon-alpha, ribavirin, normal aminotransferase values}, publisher = {Akademija medicinskih znanosti Hrvatske}, publisherplace = {Zagreb, Hrvatska} }
@article{article, author = {Pavi\'{c}, Tajana and Duvnjak, Marko}, year = {2001}, pages = {110}, keywords = {chronic hepatitis C, treatment, interferon-alpha, ribavirin, normal aminotransferase values}, title = {Interferon-alpha and ribavirin treatment in patients with chronic hepatitis C and normal aminotransferase values}, keyword = {chronic hepatitis C, treatment, interferon-alpha, ribavirin, normal aminotransferase values}, publisher = {Akademija medicinskih znanosti Hrvatske}, publisherplace = {Zagreb, Hrvatska} }




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