Napredna pretraga

Pregled bibliografske jedinice broj: 1020266

Application of adamantyl aminoguanidines infunctional self-assembled nanovesicles


Šekutor, Marina; Štimac, Adela; Tokić, Matea; Ljubetić, Ajasja; Vuletić, Tomislav; Požar, Josip; Leko, Katarina; Hanževački, Marko; Frkanec, Leo; Frkanec, Ruža
Application of adamantyl aminoguanidines infunctional self-assembled nanovesicles // 17th European Symposium on Organic Reactivity / 17th ESOR 2019
Dubrovnik, Hrvatska, 2019. str. OP-14 (predavanje, međunarodna recenzija, sažetak, znanstveni)


Naslov
Application of adamantyl aminoguanidines infunctional self-assembled nanovesicles

Autori
Šekutor, Marina ; Štimac, Adela ; Tokić, Matea ; Ljubetić, Ajasja ; Vuletić, Tomislav ; Požar, Josip ; Leko, Katarina ; Hanževački, Marko ; Frkanec, Leo ; Frkanec, Ruža

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
17th European Symposium on Organic Reactivity / 17th ESOR 2019 / - , 2019, OP-14

ISBN
978-953-55232-9-1

Skup
17th European Symposium on Organic Reactivity / 17th ESOR 2019 / Dubrovnik, Hrvatska

Mjesto i datum
Dubrovnik, Hrvatska, 08-13.09.2019

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Adamantyl aminoguanidines, model membrane systems, nanovesicles, liposomes

Sažetak
Combination of a lipophilic adamantyl subunit and a highly polar guanidine moiety affords adamantylaminoguanidines, compounds with membrane compatible features capable of binding to complementary molecules possessing phosphate groups.[1] We recently showed that adamantylaminoguanidines can effectively be incorporated into liposomes and the resulting liposomeformulations were capable of recognizing complementary liposomes.[2] We therefore turned outattention to preparing multicomponent self-assembled supramolecular nanovesicles capable of recognition and binding to fluorescently labelled DNA.[3] Our findings suggest that such nanovesicles(Figure 1) could potentially be applied as nonviral gene delivery vectors.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

Napomena
Http://esor.chem.pmf.hr/Abstracts/ESOR2019- Book_of_Abstracts_web.pdf



POVEZANOST RADA


Projekt / tema
HRZZ-IP-2018-01-6910 - Sinteza supramolekulskih samo-udruženih nanostruktura za izgradnju naprednih funkcionalnih materijala (Leo Frkanec, )
HRZZ-UIP-2017-05-9653 - Diamantoidni sustavi s heteroatomima – priprava i primjena u razvoju naprednih materijala (Marina Šekutor, )

Ustanove
Institut "Ruđer Bošković", Zagreb